دورية أكاديمية
African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo.
| العنوان: | African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo. |
|---|---|
| المؤلفون: | Smith DR; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Sprague TR; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Hollidge BS; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Valdez SM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Padilla SL; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Bellanca SA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Golden JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Coyne SR; Diagnostics Systems Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Kulesh DA; Diagnostics Systems Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Miller LJ; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Haddow AD; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Koehler JW; Diagnostics Systems Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Gromowski GD; Walter Reed Army Institute of Research, Silver Spring, Maryland., Jarman RG; Walter Reed Army Institute of Research, Silver Spring, Maryland., Alera MTP; Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand., Yoon IK; International Vaccine Institute, Seoul, Republic of Korea., Buathong R; Department of Disease Control, Bureau of Epidemiology, Ministry of Public Health, Nonthaburi, Thailand., Lowen RG; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Kane CD; Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Minogue TD; Diagnostics Systems Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Bavari S; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Tesh RB; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas.; Department of Pathology, University of Texas Medical Branch, Galveston, Texas.; Institute for Human Infections and Immunity, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas., Weaver SC; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas.; Department of Pathology, University of Texas Medical Branch, Galveston, Texas.; Institute for Human Infections and Immunity, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas., Linthicum KJ; Center for Medical, Agricultural and Veterinary Entomology, Agricultural Research Service, United States Department of Agriculture, Gainesville, Florida., Pitt ML; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland., Nasar F; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas. |
| المصدر: | The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2018 Feb; Vol. 98 (2), pp. 432-444. Date of Electronic Publication: 2017 Dec 21. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Society of Tropical Medicine and Hygiene Country of Publication: United States NLM ID: 0370507 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-1645 (Electronic) Linking ISSN: 00029637 NLM ISO Abbreviation: Am J Trop Med Hyg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Northbrook, IL : American Society of Tropical Medicine and Hygiene Original Publication: Baltimore. |
| مواضيع طبية MeSH: | Biological Variation, Population/*genetics , Zika Virus/*isolation & purification, Aedes/virology ; Africa ; Americas ; Animals ; Asia ; Disease Models, Animal ; Female ; Humans ; Mice/virology ; Mice, Inbred C57BL/virology ; Mosquito Vectors/virology ; Real-Time Polymerase Chain Reaction/methods ; Zika Virus/genetics ; Zika Virus Infection/epidemiology ; Zika Virus Infection/genetics |
| مستخلص: | Zika virus (ZIKV) is a mosquito-borne member of the genus Flavivirus that has emerged since 2007 to cause outbreaks in Africa, Asia, Oceania, and most recently, in the Americas. Here, we used an isolate history as well as genetic and phylogenetic analyses to characterize three low-passage isolates representing African (ArD 41525) and Asian (CPC-0740, SV0127-14) lineages to investigate the potential phenotypic differences in vitro and in vivo. The African isolate displayed a large plaque phenotype (∼3-4 mm) on Vero and HEK-293 cells, whereas the Asian isolates either exhibited a small plaque phenotype (∼1-2 mm) or did not produce any plaques. In multistep replication kinetics in nine different vertebrate and insect cell lines, the African isolate consistently displayed faster replication kinetics and yielded ∼10- to 10,000-fold higher peak virus titers (infectious or RNA copies) compared with the Asian isolates. Oral exposure of Aedes aegypti mosquitoes with the African isolate yielded higher infection and dissemination rates compared with the Asian isolates. Infection of Ifnar1 -/- mice with the African isolate produced a uniformly fatal disease, whereas infection with the Asian isolates produced either a delay in time-to-death or a significantly lower mortality rate. Last, the African isolate was > 10,000-fold more virulent than the Asian isolates in an interferon type I antibody blockade mouse model. These data demonstrate substantial phenotypic differences between low-passage African and Asian isolates both in vitro and in vivo and warrant further investigation. They also highlight the need for basic characterization of ZIKV isolates, as the utilization of the uncharacterized isolates could have consequences for animal model and therapeutic/vaccine development. |
| References: | J Med Entomol. 1972 Aug 1;9(4):334-7. (PMID: 5054499) J Virol. 2015 Jun;89(12):6328-37. (PMID: 25855730) N Engl J Med. 2016 Jun 2;374(22):2195-8. (PMID: 27074370) J Virol. 2001 Jan;75(2):934-42. (PMID: 11134306) J Virol. 2006 Feb;80(3):1427-39. (PMID: 16415020) J Virol. 2004 Nov;78(22):12497-507. (PMID: 15507637) Bull Soc Pathol Exot. 1993;86(1):21-8. (PMID: 8099299) Trans R Soc Trop Med Hyg. 1952 Sep;46(5):509-20. (PMID: 12995440) Clin Microbiol Infect. 2014 Oct;20(10):O595-6. (PMID: 24909208) Am J Trop Med Hyg. 2016 Jun 1;94(6):1362-9. (PMID: 27022155) Genome Announc. 2016 May 12;4(3):null. (PMID: 27174274) mSphere. 2017 May 17;2(3):. (PMID: 28529976) PLoS Negl Trop Dis. 2014 Feb 06;8(2):e2681. (PMID: 24516683) Ann Trop Med Parasitol. 1975 Mar;69(1):49-64. (PMID: 1124969) Clin Microbiol Rev. 2016 Jul;29(3):487-524. (PMID: 27029595) Euro Surveill. 2014 Mar 06;19(9):null. (PMID: 24626205) Trans R Soc Trop Med Hyg. 1952 Sep;46(5):521-34. (PMID: 12995441) PLoS Pathog. 2015 May 20;11(5):e1004874. (PMID: 25993022) Emerg Microbes Infect. 2016 Aug 24;5:e93. (PMID: 27553173) PLoS Negl Trop Dis. 2017 Jan 9;11(1):e0005296. (PMID: 28068342) Emerg Infect Dis. 2017 Aug;23 (8):1274-1281. (PMID: 28548637) J Gen Virol. 1998 Mar;79 ( Pt 3):437-46. (PMID: 9519821) Genome Announc. 2016 May 12;4(3):null. (PMID: 27174284) Cell Host Microbe. 2016 May 11;19(5):720-30. (PMID: 27066744) PLoS Pathog. 2009 Jun;5(6):e1000467. (PMID: 19503824) Bull Soc Pathol Exot Filiales. 1982 May-Jul;75(3):262-6. (PMID: 6809352) Mol Biol Evol. 2010 Feb;27(2):221-4. (PMID: 19854763) J Virol. 2005 Jul;79(13):8339-47. (PMID: 15956579) Bull Soc Pathol Exot Filiales. 1978 Mar-Apr;71(2):140-6. (PMID: 743766) Nucleic Acids Res. 2004 Mar 19;32(5):1792-7. (PMID: 15034147) Bull Soc Pathol Exot. 2001 Aug;94(3):227-30. (PMID: 11681215) Trans R Soc Trop Med Hyg. 1982;76(4):552-62. (PMID: 6304948) Emerg Infect Dis. 2015 Oct;21(10):1885-6. (PMID: 26401719) PLoS Pathog. 2011 Nov;7(11):e1002335. (PMID: 22102808) Ann Trop Med Parasitol. 1983 Apr;77(2):131-7. (PMID: 6309104) Trans R Soc Trop Med Hyg. 1981;75(3):389-93. (PMID: 6275577) J Gen Virol. 2005 Aug;86(Pt 8):2209-20. (PMID: 16033968) J Virol. 2012 Jul;86(13):7072-83. (PMID: 22532681) Emerg Infect Dis. 2015 Oct;21(10):1887. (PMID: 26403318) PLoS Med. 2017 Jan 3;14 (1):e1002203. (PMID: 28045901) J Virol. 2000 Oct;74(20):9601-9. (PMID: 11000232) Emerg Infect Dis. 2011 May;17(5):880-2. (PMID: 21529401) PLoS Negl Trop Dis. 2012;6(2):e1477. (PMID: 22389730) J Virol. 2001 Aug;75(16):7692-702. (PMID: 11462041) J Virol. 2002 Feb;76(4):1932-43. (PMID: 11799188) MBio. 2017 Mar 7;8(2):. (PMID: 28270583) N Engl J Med. 2016 Apr 21;374(16):1552-63. (PMID: 27028561) Nature. 2017 May 25;545(7655):482-486. (PMID: 28514450) Mem Inst Oswaldo Cruz. 2015 Jun;110(4):569-72. (PMID: 26061233) Bioinformatics. 1998;14(9):817-8. (PMID: 9918953) PLoS Negl Trop Dis. 2016 May 05;10 (5):e0004658. (PMID: 27149521) PLoS Pathog. 2017 Feb 16;13(2):e1006178. (PMID: 28207910) Virology. 2008 May 10;374(2):256-60. (PMID: 18395240) Am J Trop Med Hyg. 2017 Nov;97(5):1410-1417. (PMID: 28820694) Science. 2016 Apr 22;352(6284):467-70. (PMID: 27033547) PLoS Negl Trop Dis. 2016 Oct 26;10 (10 ):e0005101. (PMID: 27783679) Cell Rep. 2016 Aug 9;16(6):1485-1491. (PMID: 27481466) J Virol. 1997 Jan;71(1):291-8. (PMID: 8985349) J Hyg (Lond). 1979 Oct;83(2):213-9. (PMID: 489960) J Virol. 1998 Feb;72(2):1647-51. (PMID: 9445071) Virology. 2010 Oct 25;406(2):328-35. (PMID: 20708768) Virology. 2010 Jan 20;396(2):298-304. (PMID: 19913862) Trans R Soc Trop Med Hyg. 1983;77(4):442-5. (PMID: 6314612) J Virol. 2003 Jul;77(14):7804-13. (PMID: 12829820) Am J Trop Med Hyg. 1969 May;18(3):411-5. (PMID: 4976739) J Virol. 2008 Sep;82(17):8411-21. (PMID: 18562532) Bull Soc Pathol Exot Filiales. 1981 Sep-Oct;74(5):490-9. (PMID: 6274526) EBioMedicine. 2016 Oct;12 :161-169. (PMID: 27688094) Trans R Soc Trop Med Hyg. 1956 May;50(3):238-42. (PMID: 13337908) Trop Geogr Med. 1977 Jun;29(2):187-91. (PMID: 906078) Bull Soc Pathol Exot Filiales. 1975 May-Jun;68(3):249-58. (PMID: 1243735) N Engl J Med. 2009 Jun 11;360(24):2536-43. (PMID: 19516034) |
| تواريخ الأحداث: | Date Created: 20171228 Date Completed: 20181211 Latest Revision: 20190201 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC5929214 |
| DOI: | 10.4269/ajtmh.17-0685 |
| PMID: | 29280428 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1476-1645 |
|---|---|
| DOI: | 10.4269/ajtmh.17-0685 |