دورية أكاديمية

Serotype Distribution of Clinical Streptococcus pneumoniae Isolates before the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Cambodia.

التفاصيل البيبلوغرافية
العنوان: Serotype Distribution of Clinical Streptococcus pneumoniae Isolates before the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Cambodia.
المؤلفون: Inghammar M; Section for Infection Medicine, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.; Institut Pasteur du Cambodge, Phnom Penh, Cambodia., By Y; University of Health Science, Phnom Pen, Cambodia.; Fondation Mérieux, Phnom Penh, Cambodia., Farris C; Naval Medical Research Unit No. 2, Phnom Penh, Cambodia., Phe T; Sihanouk Hospital Center of Hope, Phnom Penh, Cambodia., Borand L; Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Kerleguer A; Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Goyet S; Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Saphonn V; University of Health Science, Phnom Pen, Cambodia., Phoeung C; University of Health Science, Phnom Pen, Cambodia., Vong S; Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Rammaert B; CHU de Poitiers, Service de Maladies Infectieuses et Tropicales, INSERM U1070, Université de Poitiers, Poitiers, France., Mayaud C; Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Guillard B; Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Yasuda C; Naval Medical Research Unit No. 2, Phnom Penh, Cambodia., Kasper MR; Naval Medical Research Unit No. 2, Phnom Penh, Cambodia., Ford G; Naval Medical Research Unit No. 2, Phnom Penh, Cambodia., Newell SW; Naval Medical Research Unit No. 2, Phnom Penh, Cambodia., An US; Cambodian National Laboratory of Public Health, Phnom Penh, Cambodia., Sokhal B; Cambodian National Laboratory of Public Health, Phnom Penh, Cambodia., Touch S; Cambodian Communicable Disease Control Department, Phnom Penh, Cambodia., Turner P; Nuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.; Cambodia Oxford Medical Research Unit, Siem Reap, Cambodia., Jacobs J; Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.; Sihanouk Hospital Center of Hope, Phnom Penh, Cambodia., Messaoudi M; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, Lyon, France., Komurian-Pradel F; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, Lyon, France., Tarantola A; Institut Pasteur du Cambodge, Phnom Penh, Cambodia.
المصدر: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2018 Mar; Vol. 98 (3), pp. 791-796. Date of Electronic Publication: 2018 Jan 04.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: American Society of Tropical Medicine and Hygiene Country of Publication: United States NLM ID: 0370507 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-1645 (Electronic) Linking ISSN: 00029637 NLM ISO Abbreviation: Am J Trop Med Hyg Subsets: MEDLINE
أسماء مطبوعة: Publication: Northbrook, IL : American Society of Tropical Medicine and Hygiene
Original Publication: Baltimore.
مواضيع طبية MeSH: Serogroup*, Pneumonia, Pneumococcal/*epidemiology , Pneumonia, Pneumococcal/*microbiology , Streptococcus pneumoniae/*classification, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/pharmacology ; Bacterial Typing Techniques ; Bronchoalveolar Lavage Fluid/microbiology ; Cambodia/epidemiology ; Child ; Child, Preschool ; Drug Resistance, Multiple, Bacterial ; Female ; Humans ; Infant ; Laboratories, Hospital ; Male ; Mass Vaccination ; Middle Aged ; Pneumococcal Vaccines ; Pneumonia, Pneumococcal/immunology ; Pneumonia, Pneumococcal/prevention & control ; Sputum/microbiology ; Streptococcus pneumoniae/drug effects ; Streptococcus pneumoniae/immunology ; Streptococcus pneumoniae/isolation & purification ; Vaccines, Conjugate
مستخلص: Childhood vaccination with the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in Cambodia in January 2015. Baseline data regarding circulating serotypes are scarce. All microbiology laboratories in Cambodia were contacted for identification of stored isolates of Streptococcus pneumoniae from clinical specimens taken before the introduction of PCV13. Available isolates were serotyped using a multiplex polymerase chain reaction method. Among 166 identified isolates available for serotyping from patients with pneumococcal disease, 4% were isolated from upper respiratory samples and 80% were from lower respiratory samples, and 16% were invasive isolates. PCV13 serotypes accounted for 60% (95% confidence interval [CI] 52-67) of all isolates; 56% (95% CI 48-64) of noninvasive and 77% (95% CI 57-89) of invasive isolates. Antibiotic resistance was more common among PCV13 serotypes. This study of clinical S. pneumoniae isolates supports the potential for high reduction in pneumococcal disease burden and may serve as baseline data for future monitoring of S. pneumoniae serotypes circulation after implementation of PCV13 childhood vaccination in Cambodia.
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المشرفين على المادة: 0 (13-valent pneumococcal vaccine)
0 (Anti-Bacterial Agents)
0 (Pneumococcal Vaccines)
0 (Vaccines, Conjugate)
تواريخ الأحداث: Date Created: 20180110 Date Completed: 20181211 Latest Revision: 20181211
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC5930902
DOI: 10.4269/ajtmh.17-0692
PMID: 29313476
قاعدة البيانات: MEDLINE
الوصف
تدمد:1476-1645
DOI:10.4269/ajtmh.17-0692