دورية أكاديمية
ADIPOQ + 45T≥G Polymorphism, Food Ingestion, and Metabolic Syndrome in Elderly Persons.
| العنوان: | ADIPOQ + 45T≥G Polymorphism, Food Ingestion, and Metabolic Syndrome in Elderly Persons. |
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| المؤلفون: | Retamoso VR; a Programa de Pós Graduação em Ciências Farmacêuticas, Universidade Federal do Pampa-Campus Uruguaiana , Uruguaiana , RS , Brasil., Maurer P; b Programa de Pós Graduação em Bioquímica, Universidade Federal do Pampa-Campus Uruguaiana , Uruguaiana , RS , Brasil., Feijóo LB; c Curso de Farmácia, Universidade Federal do Pampa-Campus Uruguaiana , Uruguaiana , RS , Brasil., Tavares GMS; d Curso de Fisioterapia, Universidade Federal do Pampa-Campus Uruguaiana , Uruguaiana , RS , Brasil., Manfredini V; b Programa de Pós Graduação em Bioquímica, Universidade Federal do Pampa-Campus Uruguaiana , Uruguaiana , RS , Brasil., Piccoli JCE; a Programa de Pós Graduação em Ciências Farmacêuticas, Universidade Federal do Pampa-Campus Uruguaiana , Uruguaiana , RS , Brasil.; b Programa de Pós Graduação em Bioquímica, Universidade Federal do Pampa-Campus Uruguaiana , Uruguaiana , RS , Brasil. |
| المصدر: | Journal of the American College of Nutrition [J Am Coll Nutr] 2018 Mar-Apr; Vol. 37 (3), pp. 209-214. Date of Electronic Publication: 2018 Jan 09. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: American College of Nutrition Country of Publication: United States NLM ID: 8215879 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-1087 (Electronic) Linking ISSN: 07315724 NLM ISO Abbreviation: J Am Coll Nutr |
| أسماء مطبوعة: | Publication: New York, NY : American College of Nutrition Original Publication: New York : Alan R. Liss, c1982- |
| مواضيع طبية MeSH: | Adiponectin/*genetics , Diet/*statistics & numerical data , Metabolic Syndrome/*epidemiology , Metabolic Syndrome/*genetics, Aged ; Cross-Sectional Studies ; Eating ; Female ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide/genetics |
| مستخلص: | Introduction: The current nutritional transition process contributes further to accelerate the onset of metabolic disorders, as do a number of environmental factors that lead to the diagnosis of chronic diseases, as a diet of low nutritional value, is possibly related to the incidence of metabolic syndrome. In addition to these factors, metabolic syndrome may also be related to genetic factors, the ADIPOQ + 45T> G polymorphism has been associated with serum adiponectin levels, insulin sensitivity, and obesity, which affects adiponectin levels act as protective factor for cardiovascular disease. In this way, the present study aimed to analyze the possible association between the ADIPOQ + 45T> G gene polymorphism, usual diet and metabolic syndrome in the elderly. Methods: We evaluated inflammatory and biochemical markers compared with older age groups (age 60 years) with and without metabolic syndrome. In addition to the anthropometric measurements of weight, height and waist circumference, the ADIPOQ + 45T> G gene polymorphism was determined by PCR- RFLP, and food consumption was investigated using a food frequency questionnaire. Results: The study included 111 elderly individuals. Our main results show that there was a significant relationship between the habitual consumption of milk for the group that had metabolic syndrome (p < 0.05). HDL-c levels, glucose, triglycerides, diastolic blood pressure and weight, height and waist circumference had to be altered in patients with metabolic syndrome. There was an association between habitual dietary intake of white meat with haplotypes TG and GG. Conclusion: We conclude that the relationship between the habitual consumption of certain food groups and ADIPOQ indicates the need for further studies to develop a better understanding of this relationship; however, there was no association between the ADIPOQ + 45T> G gene polymorphism and metabolic syndrome in the group of elderly studied. |
| فهرسة مساهمة: | Keywords: ADIPOQ gene SNP; Food consumption; adiponectin; aged; metabolic syndrome |
| المشرفين على المادة: | 0 (ADIPOQ protein, human) 0 (Adiponectin) |
| تواريخ الأحداث: | Date Created: 20180110 Date Completed: 20190814 Latest Revision: 20190814 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/07315724.2017.1386139 |
| PMID: | 29313754 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1541-1087 |
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| DOI: | 10.1080/07315724.2017.1386139 |