دورية أكاديمية
Clinico-etiologic profile of hand dermatitis and patch response of patients at a tertiary hospital in Lagos, Nigeria: results of a prospective observational study.
| العنوان: | Clinico-etiologic profile of hand dermatitis and patch response of patients at a tertiary hospital in Lagos, Nigeria: results of a prospective observational study. |
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| المؤلفون: | Otrofanowei E; Department of Medicine, Lagos University Teaching Hospital, Lagos, Nigeria., Ayanlowo OO; Department of Medicine, College of Medicine, University of Lagos, Lagos, Nigeria., Akinkugbe A; Department of Medicine, College of Medicine, University of Lagos, Lagos, Nigeria., Oresanya FA; Kyutis Clinic, Ikoyi Lagos, Nigeria. |
| المصدر: | International journal of dermatology [Int J Dermatol] 2018 Feb; Vol. 57 (2), pp. 149-155. Date of Electronic Publication: 2018 Jan 10. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: England NLM ID: 0243704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-4632 (Electronic) Linking ISSN: 00119059 NLM ISO Abbreviation: Int J Dermatol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Blackwell Science Original Publication: Philadelphia, Lippincott. |
| مواضيع طبية MeSH: | Allergens/*adverse effects , Dermatitis, Allergic Contact/*etiology , Dermatitis, Atopic/*etiology , Hand Dermatoses/*etiology, Acute Disease ; Adolescent ; Adult ; Chronic Disease ; Dermatitis, Occupational/etiology ; Female ; Hand Dermatoses/microbiology ; Humans ; Male ; Middle Aged ; Nigeria ; Patch Tests ; Prospective Studies ; Recurrence ; Tertiary Care Centers ; Young Adult |
| مستخلص: | Background: Hand dermatitis is an acute or chronic inflammation of the skin of the hands from a multifactorial cause which may be endogenous, exogenous, or a combination of both. With a wide range in severity and recurrent periods of flares, it has significant impact on the quality of life of its sufferers. A history of atopy predisposes patients to hand dermatitis, but contact dermatitis, either allergic or irritant, is the more commonly implicated factor in the etiology of hand dermatitis. Patch testing is an important tool in identifying the allergen responsible for allergic hand dermatitis, and this knowledge will contribute to improved management. Aim and Objectives: This study was undertaken to evaluate the clinical and etiologic profile and review the patch responses of patients who presented with hand dermatitis at a foremost tertiary skin clinic in the most populous state of the most populous country in Africa. Methods: A prospective, observational study in which consecutive walk-in patients who fulfilled the inclusion criteria were enrolled. Ethical clearance was obtained. Study tools included self-administered questionnaires, physical examination, and patch tests (European Hermal series), amongst others. The patch tests were carried out. Results were documented, and treatment was individualized based on clinical and investigation findings. The results were collated and analyzed with SPSS ® 17.0 edition (SPSS II). Results: Hand dermatitis was seen in 177 (13.3%) patients who presented during the study period. The mean age was 34.6 + 17.4 years. Almost two-thirds of patients (119; 67.2%) had chronic hand dermatitis, while 53 (32.8%) presented acutely. Patch responses were positive in 65 (36.7%) patients with paraphenylenediamine identified as the most frequent cause. Respondents had at least one (+) response to 20 of the 28 allergens, while there was no response to eight of the allergens in the European series. Conclusion: The study reveals that hand dermatitis is present in a younger age group and a variety of subtypes coexist. Locally sourced allergens are needed to improve the yield of patch responses. (© 2018 The International Society of Dermatology.) |
| المشرفين على المادة: | 0 (Allergens) |
| تواريخ الأحداث: | Date Created: 20180111 Date Completed: 20180807 Latest Revision: 20180807 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1111/ijd.13845 |
| PMID: | 29318580 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1365-4632 |
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| DOI: | 10.1111/ijd.13845 |