دورية أكاديمية
أعرض في EDS

Rate and Risk Factors Associated with Autism Spectrum Disorder in Congenital Diaphragmatic Hernia.

التفاصيل البيبلوغرافية
العنوان: Rate and Risk Factors Associated with Autism Spectrum Disorder in Congenital Diaphragmatic Hernia.
المؤلفون: Danzer E; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA. danzere@email.chop.edu., Hoffman C; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., D'Agostino JA; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Miller JS; Center for Autism Research, The Children's Hospital of Philadelphia, 3535 Market Street Suite 860, Philadelphia, PA, 19104-4318, USA., Waqar LN; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Gerdes M; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Bernbaum JC; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Rosenthal H; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Rintoul NE; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Herkert LM; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Peranteau WH; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Flake AW; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Adzick NS; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA., Hedrick HL; The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 5th Floor Wood Center, 3615 Civic Center Blvd, Philadelphia, PA, 19104-4318, USA.
المصدر: Journal of autism and developmental disorders [J Autism Dev Disord] 2018 Jun; Vol. 48 (6), pp. 2112-2121.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 7904301 Publication Model: Print Cited Medium: Internet ISSN: 1573-3432 (Electronic) Linking ISSN: 01623257 NLM ISO Abbreviation: J Autism Dev Disord Subsets: MEDLINE
أسماء مطبوعة: Publication: <2006- >: New York, NY : Springer
Original Publication: New York, Plenum Press.
مواضيع طبية MeSH: Autism Spectrum Disorder/*diagnosis , Autism Spectrum Disorder/*epidemiology , Hernias, Diaphragmatic, Congenital/*diagnosis , Hernias, Diaphragmatic, Congenital/*epidemiology, Child ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Infant, Newborn ; Male ; Neuropsychological Tests/standards ; Prospective Studies ; Retrospective Studies ; Risk Factors
مستخلص: To determine the rate and predictors of autism spectrum disorder (ASD) in congenital diaphragmatic hernia (CDH). Between 06/2004 and 09/2015 a total of 110 CDH survivors underwent neurodevelopmental (ND) testing and screening for ASD, followed by a full autism diagnostic evaluation if indicated at our institution. We found a 9 time higher rate of ASD in CDH children compared to the general population (P = 0.0002). Multiple patient-related and clinical variables risk factors of ASD were identified by univariate analysis. However, only short-term and long-term neurodevelopmental delays were strongly associated with ASD in CDH by multivariate comparisons. There is a striking prevalence of ASD in CDH survivors and our findings suggest that all CDH children should be regularly screened for ASD.
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فهرسة مساهمة: Keywords: Autism diagnostic observation schedule; Autism spectrum disorder; Congenital diaphragmatic hernia; Neurodevelopmental delay; Pulmonary hypertension; Pulmonary hypoplasia
تواريخ الأحداث: Date Created: 20180201 Date Completed: 20190527 Latest Revision: 20190527
رمز التحديث: 20231215
DOI: 10.1007/s10803-018-3472-6
PMID: 29383650
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-3432
DOI:10.1007/s10803-018-3472-6