دورية أكاديمية
Neuropsychological performance in patients with asymptomatic HIV-1 infection.
| العنوان: | Neuropsychological performance in patients with asymptomatic HIV-1 infection. |
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| المؤلفون: | Martínez-Banfi M; a Grupo de Neurociencias del Caribe , Universidad Simón Bolívar , Barranquilla , Colombia., Vélez JI; b Departamento de Ingeniería Industrial , Universidad del Norte , Barranquilla , Colombia., Perea MV; c Facultad de Psicología , Universidad de Salamanca , Salamanca , España., García R; c Facultad de Psicología , Universidad de Salamanca , Salamanca , España., Puentes-Rozo PJ; a Grupo de Neurociencias del Caribe , Universidad Simón Bolívar , Barranquilla , Colombia.; d Grupo de Neurociencias del Caribe, Universidad del Atlántico , Barranquilla , Colombia., Mebarak Chams M; e Departamento de Psicología, Universidad del Norte , Barranquilla , Colombia., Ladera V; c Facultad de Psicología , Universidad de Salamanca , Salamanca , España. |
| المصدر: | AIDS care [AIDS Care] 2018 May; Vol. 30 (5), pp. 623-633. Date of Electronic Publication: 2018 Feb 07. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 8915313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1360-0451 (Electronic) Linking ISSN: 09540121 NLM ISO Abbreviation: AIDS Care Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: Abingdon, Oxfordshire, U.K. : Carfax Pub. Co., c1989- |
| مواضيع طبية MeSH: | HIV-1* , Mental Processes*, Asymptomatic Diseases/*psychology , Cognition Disorders/*virology , HIV Infections/*psychology, Activities of Daily Living ; Adult ; Anxiety/virology ; Attention ; Cognition ; Depression/virology ; Female ; HIV Infections/virology ; Humans ; Learning ; Male ; Middle Aged ; Motor Skills ; Neuropsychological Tests ; Reaction Time |
| مستخلص: | Human immunodeficiency virus (HIV-1) infection and acquired immunodeficiency syndrome (AIDS) lead to neurocognitive disorders; however, there is still much knowledge to be gained regarding HIV-associated neurocognitive disorders. The purpose of this study was to assess the cognitive performance, instrumental activities of daily living, depression, and anxiety in patients with asymptomatic HIV-1 infections compared with seronegative participants without neurocognitive impairment. We studied a sample consisted of 60 patients with asymptomatic HIV-1 infections and 60 seronegative participants without neurocognitive impairment from the city of Barranquilla, Colombia, with a mean age of 36.07 years. A protocol of neuropsychological and psychopathological tests was applied to the participants. The group of patients with asymptomatic HIV infections significantly underperformed on tasks that assessed global cognitive screening, attention span, learning, phonemic verbal fluency, auditory-verbal comprehension, information processing speed, cognitive flexibility, and motor skills compared to the group of seronegative participants. No significant differences were found in memory, visual confrontation naming, vocabulary, inhibition, and instrumental activities of daily living. Additionally, the patients with asymptomatic HIV-1 infection had a higher anxiety index than the seronegative participants, but no significant difference was found in depression. A correlation was found between depression and anxiety. In conclusion, the patients with asymptomatic HIV-1 infection had lower cognitive performances than the seronegative participants in the cognitive functions mentioned above and more anxiety but still performed the instrumental activities of daily living. |
| فهرسة مساهمة: | Keywords: HIV-associated dementia; HIV-associated neurocognitive disorders; Human immunodeficiency virus; asymptomatic; neurocognitive impairment in HIV-1 |
| تواريخ الأحداث: | Date Created: 20180208 Date Completed: 20190528 Latest Revision: 20190528 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/09540121.2018.1428728 |
| PMID: | 29411628 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1360-0451 |
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| DOI: | 10.1080/09540121.2018.1428728 |