دورية أكاديمية
Demographic and histopathological patterns of neuro-epithelial brain tumors in Eastern Province of Saudi Arabia.
| العنوان: | Demographic and histopathological patterns of neuro-epithelial brain tumors in Eastern Province of Saudi Arabia. |
|---|---|
| المؤلفون: | Taha MS; Department of Neurosurgery, King Fahad Specialist Hospital, Dammam, Kingdom of Saudi Arabia. E-mail: mtaha66@hotmail.com., Almsned FM, Hasen M, Atean IM, Alwbari AM, Alharbi QK, Abdulkader MM, Almuhaish HS |
| المصدر: | Neurosciences (Riyadh, Saudi Arabia) [Neurosciences (Riyadh)] 2018 Jan; Vol. 23 (1), pp. 18-22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Armed Forces Hospital Country of Publication: Saudi Arabia NLM ID: 101252453 Publication Model: Print Cited Medium: Print ISSN: 1319-6138 (Print) Linking ISSN: 13196138 NLM ISO Abbreviation: Neurosciences (Riyadh) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Riyadh : Armed Forces Hospital |
| مواضيع طبية MeSH: | Brain Neoplasms/*epidemiology , Glioblastoma/*epidemiology, Adolescent ; Adult ; Age Factors ; Brain Neoplasms/pathology ; Child ; Child, Preschool ; Female ; Glioblastoma/pathology ; Humans ; Infant ; Male ; Middle Aged ; Neoplasm Grading ; Saudi Arabia ; Sex Factors |
| مستخلص: | Objective: To review the demographic and pathological pattern of neuro-epithelial brain tumors in a tertiary referral center in the Eastern Province of Saudi Arabia and to compare the results of our study with other national and international studies. Methods: This is a retrospective chart-review study of all patients with neuro-epithelial brain tumors referred and treated in our center between January 2010 and January 2015. The age, gender, tumor location, and histopathology were recorded. Results: The total number of cases was 149 including 96 adult cases and 53 pediatric cases. 58% of cases were male, and 42% were female. The age group distribution showed 2 peaks; one in the first 5 years of life and the second was in the age range from 26-45 years old. Glioblastoma multiforme was the most common pathological type (32%), followed by medulloblastoma (13.3%). This study showed similar results to a previous study conducted in the Eastern Province in terms of age and gender distribution, but pathologically, the tumors diagnosed in our study were generally of a higher grading. When comparing our results to other international studies in nearby countries (Jordan and Egypt), we found similarities in pathological patterns and age distribution. However, when comparing our results to a western country (USA), we found considerable differences in the age group distribution. Conclusion: Neuro-epithelial brain tumors in Saudi Arabia affect younger population according to our study compared to Western countries. These findings are similar to other studies from Middle Eastern countries. In addition, our study showed a significant increase in high grade gliomas in the Eastern Province compared to an old historical study. This increase should be interpreted cautiously due to possible selection errors, changes in pathological grading, and expertise. |
| التعليقات: | Erratum in: Neurosciences (Riyadh). 2023 Oct;28(4):283. (PMID: 37844943) |
| References: | CA Cancer J Clin. 1999 Jan-Feb;49(1):8-31, 1. (PMID: 10200775) Neurosurg Rev. 1992;15(4):295-302. (PMID: 1480276) N Engl J Med. 2001 Jan 11;344(2):114-23. (PMID: 11150363) Acta Neuropathol. 2007 Aug;114(2):97-109. (PMID: 17618441) Lancet Oncol. 2006 Mar;7(3):241-8. (PMID: 16510333) Pediatr Blood Cancer. 2006 May 1;46(5):586-96. (PMID: 16411210) J Neurol Neurosurg Psychiatry. 2004 Jun;75 Suppl 2:ii12-7. (PMID: 15146034) Neurol Clin. 2007 Nov;25(4):867-90, vii. (PMID: 17964019) Acta Neuropathol. 2016 Jun;131(6):803-20. (PMID: 27157931) |
| تواريخ الأحداث: | Date Created: 20180219 Date Completed: 20191016 Latest Revision: 20240222 |
| رمز التحديث: | 20240222 |
| مُعرف محوري في PubMed: | PMC6751907 |
| DOI: | 10.17712/nsj.2018.1.20160543 |
| PMID: | 29455216 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1319-6138 |
|---|---|
| DOI: | 10.17712/nsj.2018.1.20160543 |