دورية أكاديمية
Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species.
| العنوان: | Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species. |
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| المؤلفون: | Abastabar M; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran., Al-Hatmi AMS; Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.; Centre of Expertise in Mycology Radboud University Medical Centre/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.; Ministry of Health, Directorate General of Health Services, Ibri, Oman., Vafaei Moghaddam M; Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran., de Hoog GS; Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.; Centre of Expertise in Mycology Radboud University Medical Centre/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands., Haghani I; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran., Aghili SR; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran., Shokohi T; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran., Hedayati MT; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran., Daie Ghazvini R; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Kachuei R; Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran., Rezaei-Matehkolaei A; Department of Medical Mycology, School of Medicine, Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Makimura K; Laboratory of Space and Environmental Medicine, Graduate School of Medicine, Teikyo University, Tokyo, Japan.; Teikyo University Institute of Medical Mycology, Tokyo, Japan., Meis JF; Centre of Expertise in Mycology Radboud University Medical Centre/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.; Department of Medical Microbiology and Infectious Diseases, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands., Badali H; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran badalii@yahoo.com.; Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. |
| المصدر: | Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2018 Apr 26; Vol. 62 (5). Date of Electronic Publication: 2018 Apr 26 (Print Publication: 2018). |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, American Society for Microbiology |
| مواضيع طبية MeSH: | Antifungal Agents/*pharmacology , Fusarium/*drug effects , Fusarium/*genetics , Imidazoles/*pharmacology, Caspofungin/pharmacology ; Drug Resistance, Fungal/genetics ; Echinocandins/pharmacology ; Itraconazole/pharmacology ; Microbial Sensitivity Tests ; Triazoles/pharmacology ; Voriconazole/pharmacology |
| مستخلص: | A collection of clinical ( n = 47) and environmental ( n = 79) Fusarium isolates were tested against 10 antifungal drugs, including 2 novel imidazoles. Luliconazole and lanoconazole demonstrated very low geometric mean MIC values of 0.005 and 0.013 μg/ml, respectively, compared with 0.51 μg/ml for micafungin, 0.85 μg/ml for efinaconazole, 1.12 μg/ml for natamycin, 1.18 μg/ml for anidulafungin, 1.31 μg/ml for voriconazole, 1.35 μg/ml for caspofungin, 1.9 μg/ml for amphotericin B, and 4.08 μg/ml for itraconazole. Results show that these drugs are potential candidates for (topical) treatment of skin and nail infections due to Fusarium species. (Copyright © 2018 American Society for Microbiology.) |
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| فهرسة مساهمة: | Keywords: Fusarium species; intrinsic resistance; lanoconazole; luliconazole |
| المشرفين على المادة: | 0 (Antifungal Agents) 0 (Echinocandins) 0 (Imidazoles) 0 (Triazoles) 304NUG5GF4 (Itraconazole) 4E7858311F (latoconazole) F0XDI6ZL63 (Caspofungin) J82SB7FXWB (efinaconazole) JFU09I87TR (Voriconazole) RE91AN4S8G (luliconazole) |
| تواريخ الأحداث: | Date Created: 20180314 Date Completed: 20190618 Latest Revision: 20220408 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC5923147 |
| DOI: | 10.1128/AAC.00009-18 |
| PMID: | 29530844 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1098-6596 |
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| DOI: | 10.1128/AAC.00009-18 |