تقرير
Chemotherapy-Colchicine Interaction in a Child with Familial Mediterranean Fever and Hodgkin Lymphoma.
| العنوان: | Chemotherapy-Colchicine Interaction in a Child with Familial Mediterranean Fever and Hodgkin Lymphoma. |
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| المؤلفون: | Langenberg-Ververgaert KPS; Division of Hematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Laxer RM; Division of Rheumatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Punnett AS; Division of Hematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Dupuis LL; Department of Pharmacy, The Hospital for Sick Children, Toronto, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.; Research Institute, The Hospital for Sick Children, Toronto, Canada., Finkelstein Y; The Hospital for Sick Children, University of Toronto, Toronto, Canada., Abla O; Division of Hematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. |
| المصدر: | Mediterranean journal of hematology and infectious diseases [Mediterr J Hematol Infect Dis] 2018 Mar 01; Vol. 10 (1), pp. e2018019. Date of Electronic Publication: 2018 Mar 01 (Print Publication: 2018). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Università Cattolica del Sacro Cuore Country of Publication: Italy NLM ID: 101530512 Publication Model: eCollection Cited Medium: Print ISSN: 2035-3006 (Print) Linking ISSN: 20353006 NLM ISO Abbreviation: Mediterr J Hematol Infect Dis Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Roma, Italy : Università Cattolica del Sacro Cuore |
| مستخلص: | Familial Mediterranean fever (FMF) has been associated with hematological malignancies but has not been reported in association with Hodgkin lymphoma (HL). We hereby describe the first pediatric patient with FMF and stage IIA nodular sclerosis HL. She was treated with prednisone, doxorubicin, vincristine and etoposide (OEPA) being on therapy with colchicine. However, she suffered more than expected treatment-related toxicity attributed either to chemotherapy (severe neutropenia) or colchicine (Abdominal pains and diarrhoea). Colchicine had to be discontinued. In the absence of colchicine, she tolerated very well the second cycle of chemotherapy. Currently, she is in remission at 17 months after her HL diagnosis, and her FMF is under control with colchicine without any signs of toxicity. Competing Interests: Competing interests: The authors have declared that no competing interests exist. |
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| فهرسة مساهمة: | Keywords: Colchicine toxicity; Drugs interaction; Familial Mediterranean fever; Hodgkin lymphoma |
| تواريخ الأحداث: | Date Created: 20180314 Latest Revision: 20201001 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC5841933 |
| DOI: | 10.4084/MJHID.2018.019 |
| PMID: | 29531656 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2035-3006 |
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| DOI: | 10.4084/MJHID.2018.019 |