دورية أكاديمية
[Optimal time of surgery for acute adhesive small bowel obstruction].
| العنوان: | [Optimal time of surgery for acute adhesive small bowel obstruction]. |
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| عنوان ترانسليتريتد: | Vybor sroka operativnogo lecheniia pri ostroĭ spaechnoĭ tonkokishechnoĭ neprokhodimosti (mul'titsentrovoe prospektivnoe randomizirovannoe issledovanie). |
| المؤلفون: | Sazhin AV; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Tyagunov AE; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia; Bauman Municipal Clinical Hospital #29 of Moscow Healthcare Department, Moscow, Russia., Larichev SE; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Lebedev IS; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia; Pirogov Municipal Clinical Hospital #1 of Moscow Healthcare Department, Moscow, Russia., Makhuova GB; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia; Buyanov Municipal Clinical Hospital #12 of Moscow Healthcare Department, Moscow, Russia., Marchenko IP; Bauman Municipal Clinical Hospital #29 of Moscow Healthcare Department, Moscow, Russia., Polushkin VG; Sechenov First Moscow State Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Tyagunov AA; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Sazhin IV; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia; Buyanov Municipal Clinical Hospital #12 of Moscow Healthcare Department, Moscow, Russia., Nechay TV; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Ivakhov GB; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Titkova SM; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Anurov MV; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Gasanov MM; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia., Kolygin AV; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia; Bauman Municipal Clinical Hospital #29 of Moscow Healthcare Department, Moscow, Russia., Mirzoyan AT; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia; Bauman Municipal Clinical Hospital #29 of Moscow Healthcare Department, Moscow, Russia., Glagolev NS; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia; Bauman Municipal Clinical Hospital #29 of Moscow Healthcare Department, Moscow, Russia., Kurashinova LS; Pirogov Russian National Research Medical University of Healthcare Ministry of the Russian Federation, Moscow, Russia. |
| المصدر: | Khirurgiia [Khirurgiia (Mosk)] 2018 (3), pp. 24-30. |
| نوع المنشور: | Journal Article; Multicenter Study; Randomized Controlled Trial |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Media Sfera Country of Publication: Russia (Federation) NLM ID: 0412765 Publication Model: Print Cited Medium: Print ISSN: 0023-1207 (Print) Linking ISSN: 00231207 NLM ISO Abbreviation: Khirurgiia (Mosk) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2003->: Moskva : Media Sfera Original Publication: Moskva, Meditsina [etc.] |
| مواضيع طبية MeSH: | Intestine, Small*/pathology , Intestine, Small*/surgery, Conservative Treatment/*methods , Digestive System Surgical Procedures/*methods , Intestinal Obstruction/*surgery , Time-to-Treatment/*standards , Tissue Adhesions/*surgery, Adult ; Female ; Humans ; Intestinal Obstruction/diagnosis ; Intestinal Obstruction/etiology ; Length of Stay ; Male ; Patient Selection ; Research Design ; Tissue Adhesions/complications ; Tissue Adhesions/diagnosis |
| مستخلص: | Aim: To define optimal terms of surgery for acute adhesive non-strangulatory small bowel obstruction. Material and Methods: The analysis included 703 publications from e-LIBRARI.RU (342 works) and NCBI (361 works) databases for acute adhesive intestinal obstruction. The vast majority of articles presented retrospective analysis of single-center experience. Results: It has been established that short course of medication is predominantly used for acute adhesive intestinal obstruction in the Russian Federation. International studies point 2-5 days for conservative treatment. The advantages and disadvantages of short and long courses of medication were analyzed. Therefore, multicenter, prospective, randomized trial 'Comparison of early operative treatment (12-hour medication) and long-term conservative treatment (48 hours) for acute adhesive small bowel obstruction' (COTACSO) was planned and registered (Unique Protocol ID: 14121729). The study protocol involves clinical, laboratory and instrumental exclusion of strangulation, randomization and conservative treatment of 2 groups of patients for 12 and 48 hours. Patients will undergo surgical interventions if obstruction will be present by that date. The main endpoint is mortality rate in both groups. The end of the study is December 2020. |
| فهرسة مساهمة: | Keywords: adhesive; conservative treatment; duration of conservative treatment; small bowel obstruction; strangulation Local Abstract: [Publisher, Russian] Цель - установить оптимальный срок оперативного лечения острой спаечной нестрангуляционной тонкокишечной непроходимости. Материал и методы. Проведен анализ 703 публикаций из баз данных е-LIBRARI.RU (342 работы), NCBI (361 работа) по острой спаечной тонкокишечной непроходимости (ОСТКН), в большинстве которых представлен ретроспективный анализ работы одного медицинского центра. Результаты. Установлено, что при лечении ОСТКН в РФ используется преимущественно короткий курс консервативного лечения. По данным международных исследований, срок консервативного лечения при ОСТКН составляет 2-5 сут. Проведен анализ преимуществ и недостатков короткого и длительного курсов консервативного лечения. На основании полученных данных спланировано и зарегистрировано (Unique Protocol ID: 14121729) мультицентровое проспективное рандомизированное исследование 'Сравнительные результаты раннего оперативного лечения (12-часовой консервативный этап) и длительного консервативного лечения (48 ч) при острой спаечной тонкокишечной непроходимости' (COTACSO). Протокол исследования предусматривает клиническое, лабораторное и инструментальное исключение странгуляции, рандомизацию и консервативное лечение двух групп пациентов в течение 12 и 48 ч. При сохранении непроходимости к указанному сроку будут выполнены оперативные вмешательства. Главная конечная точка исследования - сравнение летальности в группах. Срок завершения исследования - декабрь 2020 г. |
| تواريخ الأحداث: | Date Created: 20180322 Date Completed: 20180727 Latest Revision: 20180727 |
| رمز التحديث: | 20240628 |
| DOI: | 10.17116/hirurgia2018324-30 |
| PMID: | 29560955 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0023-1207 |
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| DOI: | 10.17116/hirurgia2018324-30 |