دورية أكاديمية
Use of low-level laser therapy on children aged 1 to 5 years with energy-protein malnutrition: A clinical trial.
| العنوان: | Use of low-level laser therapy on children aged 1 to 5 years with energy-protein malnutrition: A clinical trial. |
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| المؤلفون: | Vieira KA; Department of Biophotonics, Nove de Julho University (UNINOVE), São Paulo-SP., Bastos CM; Faculty of Dentistry, CESMAC University Center, Maceió-AL, Brazil., Vitor MGC; Faculty of Dentistry, CESMAC University Center, Maceió-AL, Brazil., Deana AM; Department of Biophotonics, Nove de Julho University (UNINOVE), São Paulo-SP., Fernandes KPS; Department of Biophotonics, Nove de Julho University (UNINOVE), São Paulo-SP., Rodrigues MFSD; Department of Biophotonics, Nove de Julho University (UNINOVE), São Paulo-SP., Pavesi VCS; Department of Biophotonics, Nove de Julho University (UNINOVE), São Paulo-SP., Bussadori SK; Department of Biophotonics, Nove de Julho University (UNINOVE), São Paulo-SP. |
| المصدر: | Medicine [Medicine (Baltimore)] 2018 Apr; Vol. 97 (17), pp. e0538. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins |
| مواضيع طبية MeSH: | Child Nutrition Disorders/*complications , Lasers, Semiconductor/*therapeutic use , Low-Level Light Therapy/*methods , Protein-Energy Malnutrition/*complications , Saliva/*radiation effects , Salivary Glands/*radiation effects, Child, Preschool ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoglobulin A, Secretory/analysis ; Infant ; Male ; Nutritional Status ; Parotid Gland/radiation effects ; Saliva/immunology ; Saliva/metabolism ; Sublingual Gland/radiation effects ; Submandibular Gland/radiation effects ; Treatment Outcome |
| مستخلص: | Background: Episodes of malnutrition in early childhood can produces alterations in the salivary glands. The investigation of mechanisms that can reduce the impact of malnutrition on the defenses of the organism is of the utmost important and interest to public health. The aim of this study is to evaluate the effect of low-level laser on the saliva of children aged 1 to 5 years with energy-protein malnutrition. Methods: Mandatory inclusion criteria are diagnosis of malnutrition. The sample will consist of 50 men and women malnourished children aged 12 to 71 months. Saliva will be collected and the volume of saliva will be measured and the salivary flow rate will be determined (mL/min). Concentrations of salivary IgA in all samples will be measured using a commercial Enzyme-Linked Immunosorbent Assay (ELISA) kit. Low-level laser (laser diode) will be administered in the region of the parotid glands bilaterally as well as in the regions of the submandibular and sublingual glands. Discussion: This study will be the first that investigate the effects of local laser therapy on the salivary glands of malnourished children. Trial Registration: Clinical.trials.gov as NCT03355313, first received in 21 November 2017. |
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| سلسلة جزيئية: | ClinicalTrials.gov NCT03355313 |
| المشرفين على المادة: | 0 (Immunoglobulin A, Secretory) |
| تواريخ الأحداث: | Date Created: 20180429 Date Completed: 20180507 Latest Revision: 20240314 |
| رمز التحديث: | 20240314 |
| مُعرف محوري في PubMed: | PMC5944562 |
| DOI: | 10.1097/MD.0000000000010538 |
| PMID: | 29703031 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1536-5964 |
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| DOI: | 10.1097/MD.0000000000010538 |