دورية أكاديمية
أعرض في EDS

Work history and radioprotection practices in relation to cancer incidence and mortality in US radiologic technologists performing nuclear medicine procedures.

التفاصيل البيبلوغرافية
العنوان: Work history and radioprotection practices in relation to cancer incidence and mortality in US radiologic technologists performing nuclear medicine procedures.
المؤلفون: Bernier MO; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.; Laboratory of Epidemiology, Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France., Doody MM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Van Dyke ME; Department of Epidemiology, Emory University, Atlanta, Georgia, USA., Villoing D; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Alexander BH; Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Linet MS; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA., Kitahara CM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
المصدر: Occupational and environmental medicine [Occup Environ Med] 2018 Aug; Vol. 75 (8), pp. 533-561. Date of Electronic Publication: 2018 May 02.
نوع المنشور: Journal Article; Research Support, N.I.H., Intramural
اللغة: English
بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9422759 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1470-7926 (Electronic) Linking ISSN: 13510711 NLM ISO Abbreviation: Occup Environ Med
أسماء مطبوعة: Original Publication: London : BMJ Pub. Group, c1994-
مواضيع طبية MeSH: Health Personnel* , Neoplasms, Radiation-Induced*/epidemiology , Neoplasms, Radiation-Induced*/etiology , Neoplasms, Radiation-Induced*/mortality , Nuclear Medicine* , Occupational Diseases*/epidemiology , Occupational Diseases*/etiology , Occupational Diseases*/mortality , Occupational Exposure*/adverse effects , Radiation Protection* , Technology, Radiologic*, Adult ; Aged ; Cohort Studies ; Employment ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Neoplasms ; Procedures and Techniques Utilization ; Risk Assessment ; Surveys and Questionnaires ; United States/epidemiology
مستخلص: Introduction: Technologists working in nuclear medicine (NM) are exposed to higher radiation doses than most other occupationally exposed populations. The aim of this study was to estimate the risk of cancer in NM technologists in relation to work history, procedures performed and radioprotection practices.
Methods: From the US Radiologic Technologists cohort study, 72 755 radiologic technologists who completed a 2003-2005 questionnaire were followed for cancer mortality through 31 December 2012 and for cancer incidence through completion of a questionnaire in 2012-2013. Multivariable-adjusted models were used to estimate HRs for total cancer incidence and mortality by history of ever performing NM procedures and frequency of performing specific diagnostic or therapeutic NM procedures and associated radiation protection measures by decade.
Results: During follow-up (mean=7.5 years), 960 incident cancers and 425 cancer deaths were reported among the 22 360 technologists who worked with NM procedures. We observed no increased risk of cancer incidence (HR 0.96, 95% CI 0.89 to 1.04) or death (HR 1.05, 95% CI 0.93 to 1.19) among workers who ever performed NM procedures. HRs for cancer incidence but not mortality were higher for technologists who began performing therapeutic procedures in 1960 and later compared with the 1950s. Frequency of performing diagnostic or therapeutic NM procedures and use of radioprotection measures were not consistently associated with cancer risk. No clear associations were observed for specific cancers, but results were based on small numbers.
Conclusion: Cancer incidence and mortality were not associated with NM work history practices, including greater frequency of procedures performed.
Competing Interests: Competing interests: None declred.
(© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)
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معلومات مُعتمدة: Z99 CA999999 United States Intramural NIH HHS; ZIA CP010133-21 United States Intramural NIH HHS
فهرسة مساهمة: Keywords: cancer; cohort study; ionising radiation; nuclear medicine
تواريخ الأحداث: Date Created: 20180504 Date Completed: 20190725 Latest Revision: 20240328
رمز التحديث: 20240329
مُعرف محوري في PubMed: PMC6051924
DOI: 10.1136/oemed-2017-104559
PMID: 29720482
قاعدة البيانات: MEDLINE
الوصف
تدمد:1470-7926
DOI:10.1136/oemed-2017-104559