دورية أكاديمية
Evolution of gamma knife capsulotomy for intractable obsessive-compulsive disorder.
| العنوان: | Evolution of gamma knife capsulotomy for intractable obsessive-compulsive disorder. |
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| المؤلفون: | Miguel EC; Department and Institute of Psychiatry, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil. ecmiguel@usp.br., Lopes AC; Department and Institute of Psychiatry, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil., McLaughlin NCR; Departments of Psychiatry and Human Behavior and Neurosurgery, Warren Alpert Medical School of Brown University and Veterans Affairs Medical Center of Providence, Providence, RI, USA., Norén G; Departments of Psychiatry and Human Behavior and Neurosurgery, Warren Alpert Medical School of Brown University and Veterans Affairs Medical Center of Providence, Providence, RI, USA., Gentil AF; Department and Institute of Psychiatry, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil., Hamani C; Division of Neurosurgery, Sunnybrook Health Sciences Centre, Harquail Centre for Neuromodulation, University of Toronto, Toronto, Ontario, Canada., Shavitt RG; Department and Institute of Psychiatry, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil., Batistuzzo MC; Department and Institute of Psychiatry, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil., Vattimo EFQ; Department and Institute of Psychiatry, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil., Canteras M; Discipline of Neurosurgery, Universidade Federal de São Paulo, São Paulo, SP, Brazil., De Salles A; Hospital do Coração, São Paulo, Brazil., Gorgulho A; Hospital do Coração, São Paulo, Brazil., Salvajoli JV; Hospital do Coração, São Paulo, Brazil., Fonoff ET; Department of Neurology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil., Paddick I; National Hospital for Neurology and Neurosurgery, London, UK., Hoexter MQ; Department and Institute of Psychiatry, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil., Lindquist C; Gamma Knife Centre, BUPA Cromwell Hospital, London, UK., Haber SN; University of Rochester School of Medicine, Rochester, New York, USA.; McLean Hospital, Harvard University, Boston, USA., Greenberg BD; Departments of Psychiatry and Human Behavior and Neurosurgery, Warren Alpert Medical School of Brown University and Veterans Affairs Medical Center of Providence, Providence, RI, USA., Sheth SA; Discipline of Neurosurgery, Universidade Federal de São Paulo, São Paulo, SP, Brazil. |
| المصدر: | Molecular psychiatry [Mol Psychiatry] 2019 Feb; Vol. 24 (2), pp. 218-240. Date of Electronic Publication: 2018 May 09. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2000- : Houndmills, Basingstoke, UK : Nature Publishing Group Specialist Journals Original Publication: Houndmills, Hampshire, UK ; New York, NY : Stockton Press, c1996- |
| مواضيع طبية MeSH: | Internal Capsule/*surgery , Obsessive-Compulsive Disorder/*surgery , Obsessive-Compulsive Disorder/*therapy, Frontal Lobe/physiopathology ; Humans ; Neural Pathways/physiopathology ; Neuropsychological Tests ; Neurosurgical Procedures/methods ; Obsessive-Compulsive Disorder/physiopathology ; Radiosurgery/methods ; Treatment Outcome |
| مستخلص: | For more than half a century, stereotactic neurosurgical procedures have been available to treat patients with severe, debilitating symptoms of obsessive-compulsive disorder (OCD) that have proven refractory to extensive, appropriate pharmacological, and psychological treatment. Although reliable predictors of outcome remain elusive, the establishment of narrower selection criteria for neurosurgical candidacy, together with a better understanding of the functional neuroanatomy implicated in OCD, has resulted in improved clinical efficacy for an array of ablative and non-ablative intervention techniques targeting the cingulum, internal capsule, and other limbic regions. It was against this backdrop that gamma knife capsulotomy (GKC) for OCD was developed. In this paper, we review the history of this stereotactic radiosurgical procedure, from its inception to recent advances. We perform a systematic review of the existing literature and also provide a narrative account of the evolution of the procedure, detailing how the procedure has changed over time, and has been shaped by forces of evidence and innovation. As the procedure has evolved and adverse events have decreased considerably, favorable response rates have remained attainable for approximately one-half to two-thirds of individuals treated at experienced centers. A reduction in obsessive-compulsive symptom severity may result not only from direct modulation of OCD neural pathways but also from enhanced efficacy of pharmacological and psychological therapies working in a synergistic fashion with GKC. Possible complications include frontal lobe edema and even the rare formation of delayed radionecrotic cysts. These adverse events have become much less common with new radiation dose and targeting strategies. Detailed neuropsychological assessments from recent studies suggest that cognitive function is not impaired, and in some domains may even improve following treatment. We conclude this review with discussions covering topics essential for further progress of this therapy, including suggestions for future trial design given the unique features of GKC therapy, considerations for optimizing stereotactic targeting and dose planning using biophysical models, and the use of advanced imaging techniques to understand circuitry and predict response. GKC, and in particular its modern variant, gamma ventral capsulotomy, continues to be a reliable treatment option for selected cases of otherwise highly refractory OCD. |
| References: | JAMA Psychiatry. 2016 Mar;73(3):268-274. (PMID: 26818216) World Neurosurg. 2013 Sep-Oct;80(3-4):S31.e9-16. (PMID: 23159652) Stereotact Funct Neurosurg. 2010;88(3):177-82. (PMID: 20431329) J Neurosurg. 1962 Feb;19:89-100. (PMID: 13893868) Aust N Z J Psychiatry. 2013 Feb;47(2):121-41. (PMID: 23125399) J Neurosurg. 2013 Nov;119(5):1112-8. (PMID: 23829816) J Neurosurg. 2014 Jul;121(1):123-30. (PMID: 24702323) J Neuropsychiatry Clin Neurosci. 2012 Spring;24(2):176-82. (PMID: 22772665) Lancet Psychiatry. 2016 Aug;3(8):730-739. (PMID: 27318812) J Neurosci. 2018 Feb 21;38(8):2106-2117. (PMID: 29358360) J Neurosci Methods. 2000 Jan 15;94(2):165-75. (PMID: 10661836) Br J Psychiatry. 1973 Aug;123(573):133-40. (PMID: 4582234) Neurosurgery. 1997 Aug;41(2):396-401; discussion 401-2. (PMID: 9257307) Lancet Psychiatry. 2016 Nov;3(11):1059-1066. (PMID: 27726982) Arch Gen Psychiatry. 2005 Mar;62(3):301-9. (PMID: 15753243) J Nucl Med. 2014 Jun;55(6):951-9. (PMID: 24722531) Hum Brain Mapp. 2017 Dec;38(12):6107-6117. (PMID: 28913860) J Anxiety Disord. 2016 Aug;42:45-51. (PMID: 27268401) Mol Psychiatry. 2005 Mar;10(3):258-75. (PMID: 15611786) Br J Surg. 1964 Feb;51:114-24. (PMID: 14117767) J Neurosurg. 2015 May;122(5):1028-37. (PMID: 25635480) Lakartidningen. 1978 Feb 15;75(7):547-9. (PMID: 342844) Neurosurgery. 2014 Oct;75(4):327-33; quiz 333. (PMID: 25050579) J Neuropsychiatry Clin Neurosci. 2009 Fall;21(4):381-92. (PMID: 19996246) J Neuropsychiatry Clin Neurosci. 1997 Summer;9(3):471-81. (PMID: 9276848) Mol Psychiatry. 2010 Jan;15(1):64-79. (PMID: 18490925) Am J Epidemiol. 2013 Nov 1;178(9):1366-77. (PMID: 24091891) Lancet. 1999 Oct 30;354(9189):1526. (PMID: 10551504) J Clin Psychiatry. 2002 Jan;63(1):21-7. (PMID: 11838621) Psychiatry Res. 2015 Feb 28;225(3):236-46. (PMID: 25613661) J Psychiatr Res. 2014 Oct;57:141-8. (PMID: 25012187) World Psychiatry. 2016 Feb;15(1):80-1. (PMID: 26833615) Neurocase. 2014;20(1):42-5. (PMID: 23057416) Turk Neurosurg. 2014;24(4):583-6. (PMID: 25050687) J Neurosurg. 1967 May;26(5):488-95. (PMID: 5337782) Neurosci Lett. 2008 Dec 12;447(2-3):138-42. (PMID: 18835422) Cereb Cortex. 2000 Nov;10(11):1078-92. (PMID: 11053229) Brain. 2010 Jul;133(Pt 7):2098-114. (PMID: 20558415) Psychopharmacol Bull. 1986;22(2):343-81. (PMID: 3774930) Lancet. 1952 Mar 8;1(6706):475-81. (PMID: 14898782) Braz J Psychiatry. 2003 Mar;25(1):43-50. (PMID: 12975679) Ann N Y Acad Sci. 1999 Jun 29;877:33-48. (PMID: 10415641) Neuropsychopharmacology. 2010 Jan;35(1):317-36. (PMID: 19759530) Brain Res. 1976 Jun 25;110(1):21-38. (PMID: 819108) Arch Gen Psychiatry. 1989 Nov;46(11):1006-11. (PMID: 2684084) Biol Psychiatry. 2018 Sep 1;84(5):355-364. (PMID: 29361268) Stereotact Funct Neurosurg. 1991;57(1-2):72-81. (PMID: 1725560) Mov Disord. 2016 Mar;31(3):290-6. (PMID: 26952118) J Clin Psychiatry. 2000 Feb;61(2):150-6; quiz 157. (PMID: 10732667) Neurosurgery. 1999 Mar;44(3):452-8; discussion 458-60. (PMID: 10069581) CNS Spectr. 2004 Nov;9(11):833-47. (PMID: 15520607) J Neurosurg. 2013 Mar;118(3):491-7. (PMID: 23240700) Brain Res. 1975 Feb 7;84(2):169-80. (PMID: 803392) Depress Anxiety. 2007;24(6):440-6. (PMID: 17096398) Brain Imaging Behav. 2016 Dec;10(4):1054-1067. (PMID: 26518214) Am J Psychiatry. 1999 Sep;156(9):1409-16. (PMID: 10484953) BMJ Open. 2017 Jun 6;7(5):e013133. (PMID: 28588105) J Clin Psychopharmacol. 2001 Oct;21(5):488-92. (PMID: 11593074) J Affect Disord. 2006 Aug;94(1-3):199-209. (PMID: 16764938) J Anxiety Disord. 2012 Jan;26(1):25-31. (PMID: 21907540) Neurosurg Focus. 2008;25(1):E3. (PMID: 18590380) Psychiatry Res. 2015 May 30;227(1):114-25. (PMID: 25681005) Nat Rev Neurosci. 2011 Oct 20;12(11):652-69. (PMID: 22011681) Arch Gen Psychiatry. 2010 Oct;67(10):1061-8. (PMID: 20921122) Curr Psychiatry Rep. 2012 Jun;14(3):211-9. (PMID: 22527872) Br J Psychiatry. 1973 Aug;123(573):141-8. (PMID: 4582235) J Neurosurg. 2014 Jan;120(1):152-163. (PMID: 24236652) J Clin Psychiatry. 2015 Dec;76(12):e1605-10. (PMID: 26717540) Int J Neuropsychopharmacol. 2012 Sep;15(8):1173-91. (PMID: 22226028) Soc Sci Med. 1998 Jun;46(12):1569-85. (PMID: 9672396) J Neurol Neurosurg Psychiatry. 1983 Sep;46(9):797-803. (PMID: 6352865) Mol Psychiatry. 2018 Apr;23(4):843-849. (PMID: 28397839) J Neurosci. 2011 Jul 13;31(28):10392-402. (PMID: 21753016) Depress Anxiety. 2013 Aug;30(8):763-72. (PMID: 23109056) Med Care. 1992 Jun;30(6):473-83. (PMID: 1593914) Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 2;81:161-168. (PMID: 29100975) World Neurosurg. 2013 Sep-Oct;80(3-4):S32.e1-9. (PMID: 23872618) World Neurosurg. 2020 Sep;141:e941-e952. (PMID: 32565377) Clin Psychol Rev. 2004 Dec;24(8):1011-30. (PMID: 15533282) J Neurol Neurosurg Psychiatry. 1965 Aug;28:304-10. (PMID: 14338119) J Neurosci. 2013 Feb 13;33(7):3190-201. (PMID: 23407972) JAMA. 2017 Apr 4;317(13):1358-1367. (PMID: 28384832) Eur Neuropsychopharmacol. 2012 Jun;22(6):406-14. (PMID: 22209362) Arch Gen Psychiatry. 1999 Feb;56(2):121-7. (PMID: 10025435) Arch Gen Psychiatry. 2008 Aug;65(8):914-21. (PMID: 18678796) J Psychiatr Res. 2011 May;45(5):687-90. (PMID: 20965515) Depress Anxiety. 2010 Jun;27(6):556-72. (PMID: 20336805) Neurosurgery. 2004 Jul;55(1):168-72; discussion 172-3. (PMID: 15214986) JAMA Psychiatry. 2015 Feb;72(2):127-35. (PMID: 25536384) Nat Rev Neurosci. 2014 Jun;15(6):410-24. (PMID: 24840803) Neuropsychopharmacology. 2015 Jul;40(8):1837-45. (PMID: 25645373) Braz J Psychiatry. 2004 Mar;26(1):8-9. (PMID: 15057833) Neurosurgery. 1995 Feb;36(2):294-302. (PMID: 7731509) Science. 1947 Oct 10;106(2754):349-50. (PMID: 17777432) J Neurosurg. 2017 Jan;126(1):132-147. (PMID: 27035167) J Neurol Neurosurg Psychiatry. 2014 Sep;85(9):1003-8. (PMID: 24444853) Acta Chir Scand. 1951 Dec 13;102(4):316-9. (PMID: 14914373) Mol Psychiatry. 2017 Nov;22(11):1626-1632. (PMID: 27431293) Mol Psychiatry. 2015 Oct;20(10):1205-11. (PMID: 25421403) Neurosurgery. 2011 Jan;68(1):28-32; discussion 23-3. (PMID: 21150752) Behav Cogn Psychother. 2009 Oct;37(5):485-96. (PMID: 19796435) Neurosurgery. 2007 Sep;61(3 Suppl):130-40; discussion 140-1. (PMID: 17876243) J Neurosurg. 2016 Jan;124(1):77-89. (PMID: 26252455) J Clin Psychiatry. 2010 Aug;71(8):1033-9. (PMID: 20797381) JAMA Psychiatry. 2014 Sep;71(9):1066-76. (PMID: 25054836) J Comp Neurol. 2004 Oct 18;478(3):248-68. (PMID: 15368534) Mol Psychiatry. 2010 Jan;15(1):53-63. (PMID: 18725912) Schizophr Bull. 1988;14(2):179-83. (PMID: 3059467) J Neuropsychiatry Clin Neurosci. 2014 Winter;26(1):81-6. (PMID: 24515679) |
| معلومات مُعتمدة: | P50 MH106435 United States MH NIMH NIH HHS |
| تواريخ الأحداث: | Date Created: 20180511 Date Completed: 20200106 Latest Revision: 20240720 |
| رمز التحديث: | 20240720 |
| مُعرف محوري في PubMed: | PMC6698394 |
| DOI: | 10.1038/s41380-018-0054-0 |
| PMID: | 29743581 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1476-5578 |
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| DOI: | 10.1038/s41380-018-0054-0 |