دورية أكاديمية

The Impact of Atrial Fibrillation Clinical Subtype on Mortality.

التفاصيل البيبلوغرافية
العنوان: The Impact of Atrial Fibrillation Clinical Subtype on Mortality.
المؤلفون: Leung M; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands; Department of Cardiology, Ingham Institute at Liverpool Hospital, University of New South Wales, Sydney, Australia., van Rosendael PJ; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands., Abou R; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands., Ajmone Marsan N; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands., Leung DY; Department of Cardiology, Ingham Institute at Liverpool Hospital, University of New South Wales, Sydney, Australia., Delgado V; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands., Bax JJ; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands. Electronic address: j.j.bax@lumc.nl.
المصدر: JACC. Clinical electrophysiology [JACC Clin Electrophysiol] 2018 Feb; Vol. 4 (2), pp. 221-227. Date of Electronic Publication: 2017 Nov 06.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101656995 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-5018 (Electronic) Linking ISSN: 2405500X NLM ISO Abbreviation: JACC Clin Electrophysiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [New York, NY] : Elsevier Inc., [2015]-
مواضيع طبية MeSH: Atrial Fibrillation*/classification , Atrial Fibrillation*/diagnosis , Atrial Fibrillation*/mortality, Aged ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Retrospective Studies
مستخلص: Objectives: This study sought to investigate the prognostic implications of the clinical subtype of atrial fibrillation (AF): paroxysmal or persistent.
Background: Underlying structural abnormalities of the left atrium may be responsible for the initial clinical presentation of AF in either paroxysmal or persistent form, yet the prognostic implications of the clinical subtype on presentation are unknown.
Methods: Over a median of 7 years, 1,773 patients (age 64 ± 12 years, 74% males) with nonvalvular AF with index presentations for paroxysmal or persistent AF were followed for the occurrence of all-cause mortality. Clinical information including cardiovascular risk factors, comorbid diseases associated with AF, and CHA 2 DS 2 -VASc (congestive heart failure, hypertension, age ≥75 [double weight], diabetes, stroke [double weight], vascular disease, age 65-74, and sex category [female]) score was collected and analyzed.
Results: In this study, 1,005 patients (57%) had persistent AF. Eighty patients (10%) with paroxysmal AF and 174 patients (17%) with persistent AF died during the follow-up period. Persistent AF compared with paroxysmal AF upon initial AF diagnosis was independently associated with worse survival independent of the CHA 2 DS 2 -VASc score and other high-risk cardiovascular risk factors (hazard ratio: 1.24; 95% confidence interval: 1.11 to 1.38).
Conclusions: In patients with nonvalvular AF, persistent AF compared with paroxysmal AF upon first diagnosis is independently associated with increased mortality.
(Copyright © 2018 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)
التعليقات: Comment in: JACC Clin Electrophysiol. 2018 Feb;4(2):228-230. (PMID: 29749942)
فهرسة مساهمة: Keywords: atrial fibrillation; mortality; prognosis
تواريخ الأحداث: Date Created: 20180512 Date Completed: 20191007 Latest Revision: 20191007
رمز التحديث: 20231215
DOI: 10.1016/j.jacep.2017.09.002
PMID: 29749941
قاعدة البيانات: MEDLINE
الوصف
تدمد:2405-5018
DOI:10.1016/j.jacep.2017.09.002