دورية أكاديمية
Liposomal bupivacaine reduces opioid consumption and length of stay in patients undergoing primary total hip arthroplasty.
| العنوان: | Liposomal bupivacaine reduces opioid consumption and length of stay in patients undergoing primary total hip arthroplasty. |
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| المؤلفون: | VanWagner MJ; 1 Department of Orthopaedic Surgery, McLaren Macomb Medical Center, Mount Clemens, MI, USA., Krebs NM; 1 Department of Orthopaedic Surgery, McLaren Macomb Medical Center, Mount Clemens, MI, USA., Corser W; 2 Michigan State University, College of Osteopathic Medicine, East Lansing, MI, USA., Johnson CN; 1 Department of Orthopaedic Surgery, McLaren Macomb Medical Center, Mount Clemens, MI, USA.; 3 Ortho Northeast, Parkview Cancer Institute, Fort Wayne, IN, USA. |
| المصدر: | Hip international : the journal of clinical and experimental research on hip pathology and therapy [Hip Int] 2019 May; Vol. 29 (3), pp. 276-281. Date of Electronic Publication: 2018 May 29. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publishing Country of Publication: United States NLM ID: 9200413 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1724-6067 (Electronic) Linking ISSN: 11207000 NLM ISO Abbreviation: Hip Int Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2018- : Thousand Oaks, CA : SAGE Publishing Original Publication: Milano, Italy : Wichtig, c1991- |
| مواضيع طبية MeSH: | Analgesics, Opioid/*therapeutic use , Arthroplasty, Replacement, Hip/*adverse effects , Bupivacaine/*administration & dosage , Length of Stay/*trends , Pain Management/*methods , Pain, Postoperative/*drug therapy, Aged ; Anesthetics, Local/administration & dosage ; Female ; Humans ; Intraoperative Period ; Liposomes ; Male ; Middle Aged ; Pain, Postoperative/etiology ; Retrospective Studies |
| مستخلص: | Background: Optimising postoperative pain management after total hip arthroplasty (THA) has been associated with improved patient outcomes. However, conclusions regarding the role of liposomal bupivacaine (LB) during THA remain mixed. The purpose of this study was to determine whether substituting a standard intraoperative wound infiltrate with LB as part of a multimodal pain management protocol would decrease subsequent opioid consumption and overall length of hospital stay in patients undergoing primary THA. Methods: Data was retrospectively collected on 170 consecutive patients who underwent primary THA at a single institution from January 2014 to October 2014. Outcomes from the first 85 patients who received intraoperative LB were compared to the prior 85 patients who received a standard intraoperative "cocktail" without LB. The remainder of the multimodal pain management protocol was identical between groups. Results: Total continuous and categorical postoperative hospital opioid consumption rates in the LB subgroup were significantly lower than the non-LB subgroup ( p < 0.001). The use of LB was associated with a relative reduction in opioid consumption on the day of surgery ( p = 0.001), postoperative day 1 ( p < 0.001), postoperative day 2 ( p < 0.001) and postoperative day 3 ( p < 0.001). Patients who received LB had decreased length of stay ( p = 0.001) and were discharged on lower doses of opioids. Conclusion: Substituting to LB from a standard wound infiltrate during primary THA, in addition to our standard multimodal pain management protocol, resulted in significantly lower postoperative opioid consumption and decreased length of stay. |
| فهرسة مساهمة: | Keywords: Bupivacaine; liposomal; multimodal; pain; periarticular injection; total hip arthroplasty |
| المشرفين على المادة: | 0 (Analgesics, Opioid) 0 (Anesthetics, Local) 0 (Liposomes) Y8335394RO (Bupivacaine) |
| تواريخ الأحداث: | Date Created: 20180530 Date Completed: 20191202 Latest Revision: 20220408 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1177/1120700018778240 |
| PMID: | 29808726 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1724-6067 |
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| DOI: | 10.1177/1120700018778240 |