دورية أكاديمية
Classifying sepsis patients in the emergency department using SIRS, qSOFA or MEWS.
| العنوان: | Classifying sepsis patients in the emergency department using SIRS, qSOFA or MEWS. |
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| المؤلفون: | van der Woude SW; Faculty of Medicine, University of Amsterdam, Amsterdam, the Netherlands., van Doormaal FF, Hutten BA, J Nellen F, Holleman F |
| المصدر: | The Netherlands journal of medicine [Neth J Med] 2018 May; Vol. 76 (4), pp. 158-166. |
| نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Van Zuiden Communications Country of Publication: Netherlands NLM ID: 0356133 Publication Model: Print Cited Medium: Internet ISSN: 1872-9061 (Electronic) Linking ISSN: 03002977 NLM ISO Abbreviation: Neth J Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2002- : Alphen aan de Rijn, The Netherlands : Van Zuiden Communications Original Publication: Haarlem, Bohn |
| مواضيع طبية MeSH: | Emergency Service, Hospital* , Hospital Mortality* , Severity of Illness Index*, Sepsis/*classification , Sepsis/*diagnosis, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sensitivity and Specificity ; Young Adult |
| مستخلص: | Objective: To determine the effect of qSOFA and SOFA compared with the MEWS and SIRS criteria on the classification of emergency department (ED) patients with an infection as having sepsis. Methods: A retrospective single-centre study was performed in a random sample of 600 medical patients who visited the ED of the Academic Medical Centre Amsterdam between 1 November 2015 and 1 November 2016. Data for the different sepsis scores, as well as general data and demographics were retrieved. Descriptive analytics and sensitivity/specificity analysis were used to evaluate the performance of the different sepsis tools. Results: Of 577 evaluable medical patients, 198 patients (34.3%) had a probable infection. The SIRS sepsis criteria, severe sepsis criteria, MEWS ≥ 5 and qSOFA criteria classified 141/198 (71.2%), 55/198 (27.8%), 58/198 (29.3%) and 17/198 patients (8.6%) respectively, as septic. The in-hospital mortality of patients classified as septic by the SIRS and qSOFA score was 6.4% and 29.4%. The qSOFA and SIRS score of ≥ 2 had a specificity of 93.7% (95% CI: 91.3-95.6) and 56.9% (52.7-61.1) in predicting in-hospital mortality. Conclusion: No major differences in gender, age, comorbidity and site of infection between patients with sepsis or severe sepsis classified by the SIRS, qSOFA criteria or MEWS of ≥ 5 were found. The qSOFA criteria classifies a smaller group of patients as septic compared with the SIRS or MEWS. Due to this strict selection, the qSOFA score seems unsuitable as a bedside tool in the work-up and treatment of sepsis at the ED. |
| تواريخ الأحداث: | Date Created: 20180531 Date Completed: 20191014 Latest Revision: 20191014 |
| رمز التحديث: | 20240628 |
| PMID: | 29845938 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1872-9061 |
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