دورية أكاديمية
The association between liver cirrhosis and fracture risk: A systematic review and meta-analysis.
| العنوان: | The association between liver cirrhosis and fracture risk: A systematic review and meta-analysis. |
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| المؤلفون: | Liang J; Nanfang Hospital, Southern Medical University, Guangzhou, China., Meng WD; Nanfang Hospital, Southern Medical University, Guangzhou, China., Yang JM; Nanfang Hospital, Southern Medical University, Guangzhou, China., Li SL; Nanfang Hospital, Southern Medical University, Guangzhou, China., Zhong MN; Changde Third People's Hospital of Hunan, Changde, China., Hou XX; Nanfang Hospital, Southern Medical University, Guangzhou, China., Wang R; Nanfang Hospital, Southern Medical University, Guangzhou, China., Long YY; Shaoyang Maternal and Child Health Care Hospital of Hunan, Shaoyang, China., Bao LX; Nanfang Hospital, Southern Medical University, Guangzhou, China., Bao M; Nanfang Hospital, Southern Medical University, Guangzhou, China. |
| المصدر: | Clinical endocrinology [Clin Endocrinol (Oxf)] 2018 Oct; Vol. 89 (4), pp. 408-413. Date of Electronic Publication: 2018 Aug 09. |
| نوع المنشور: | Journal Article; Meta-Analysis; Review; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Publishing Country of Publication: England NLM ID: 0346653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2265 (Electronic) Linking ISSN: 03000664 NLM ISO Abbreviation: Clin Endocrinol (Oxf) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2003->: Oxford : Blackwell Publishing Original Publication: Oxford, Blackwell Scientific Publications. |
| مواضيع طبية MeSH: | Fractures, Bone/*epidemiology , Liver Cirrhosis/*epidemiology, Animals ; Confidence Intervals ; Hip Fractures/epidemiology ; Humans ; Odds Ratio ; Risk Factors |
| مستخلص: | Objective: Liver cirrhosis (LC) was associated with an increased risk of osteoporosis; however, the association between LC and fracture risk was inconclusive. Therefore, this systematic review and meta-analysis aims to explore the association between LC and fracture risk. Design: To identify related literature, a systematic search of PubMed, EMBASE, Web of science and the Cochrane Library from 1965 to July 2017 without language limitation was performed. The random-effects model described by DerSimonian and Laird was used to calculate pooled odds ratios (ORs) and 95% confidence intervals (CIs). Results: Eventually, 5 cohort and 3 case-control studies were identified, which included 321 035 subjects and 31 272 fracture cases. The pooled OR of the association between LC and any fracture risk, hip fracture, spine/trunk fracture and limb fracture was 1.94 (95% CI, 1.59-2.37), 2.11 (95% CI, 1.34-3.32), 2.00 (95% CI, 1.50-2.67) and 1.82 (95% CI, 1.65-2.01), respectively. Conclusion: In conclusion, this study indicates that cirrhotic patients have an increased risk of fracture. Preventive measures should be instituted as early as possible. (© 2018 John Wiley & Sons Ltd.) |
| فهرسة مساهمة: | Keywords: cirrhosis; fracture; meta-analysis; primary biliary cirrhosis |
| تواريخ الأحداث: | Date Created: 20180610 Date Completed: 20191108 Latest Revision: 20230918 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1111/cen.13762 |
| PMID: | 29885255 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1365-2265 |
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| DOI: | 10.1111/cen.13762 |