دورية أكاديمية
PATHOPHYSIOLOGICAL ASPECTS OF PLEIOTROPIC EFFECTS OF GASTROINTESTINAL HORMONES.
| العنوان: | PATHOPHYSIOLOGICAL ASPECTS OF PLEIOTROPIC EFFECTS OF GASTROINTESTINAL HORMONES. |
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| المؤلفون: | Korniushyn OV, Toropova JG, Semikova GV, Neimark AE, Dora SV, Davidova EE, Carelli L, Tkachuk OV, Markitantova AS |
| المصدر: | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology [Eksp Klin Gastroenterol] 2016 (10), pp. 4-14. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English; Russian |
| بيانات الدورية: | Publisher: Global Media Technologies Country of Publication: Russia (Federation) NLM ID: 101144944 Publication Model: Print Cited Medium: Print ISSN: 1682-8658 (Print) Linking ISSN: 16828658 NLM ISO Abbreviation: Eksp Klin Gastroenterol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2015-> : Moscow : Global Media Technologies Original Publication: Moskva : Anakharsis |
| مواضيع طبية MeSH: | Biomimetic Materials*/metabolism , Biomimetic Materials*/therapeutic use , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/metabolism , Gastrointestinal Hormones*/metabolism , Gastrointestinal Hormones*/therapeutic use, Animals ; Humans |
| مستخلص: | The unique properties and a great therapeutic potential of incretin drugs allowed them to win a firm place in modern algorithms of treatment of type 2 diabetes in an unprecedented short period of time. Due to discovery of the incretin effect and introduction of the increrin mimetics into clinical practice, an interest of the researchers was growing to study the plelotropic effects of gastrointestinal hormones. In experimental and clinical studies in recent years there has been shown the cytoprotective and cytoproliferative effects of a number of intestinal hormones, namely giucagon-like peptide-1 (GLP-1), ghrelin, and obestatin when administered systemicallyThis review presents an analysis of the currently available results of fundamental and clinical research on the plelotropic potential of the gastrointestinal peptides, and also determines the relevance of further research on the metabolic effects of bariatric surgery. |
| المشرفين على المادة: | 0 (Gastrointestinal Hormones) |
| تواريخ الأحداث: | Date Created: 20180612 Date Completed: 20180709 Latest Revision: 20180709 |
| رمز التحديث: | 20240628 |
| PMID: | 29889364 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1682-8658 |
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