دورية أكاديمية

Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus.

التفاصيل البيبلوغرافية
العنوان: Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus.
المؤلفون: Evers AWM; Health, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, Leiden, the Netherlands., Colloca L; Departments of Pain Translational Symptoms Science and Anaesthesiology, School of Nursing and Medicine, University of Maryland Baltimore, Baltimore, Maryland, USA., Blease C; General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Annoni M; Institute of Biomedical Technologies, National Research Council, Rome, Italy., Atlas LY; Section on Affective Neuroscience and Pain, NIH, Bethesda, Massachusetts, USA., Benedetti F; Physiology and Neuroscience, University of Turin Medical School, Turin, Italy., Bingel U; Department of Neurology, University Hospital Essen, Essen, Germany., Büchel C; Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Carvalho C; Department of Clinical and Health Psychology, Instituto Universitário de Ciências Psicológicas, Lisbon, Portugal., Colagiuri B; School of Psychology, University of Sydney, Sydney, New South Wales, Australia., Crum AJ; Department of Psychology, Stanford University, Stanford, California, USA., Enck P; Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany., Gaab J; Faculty of Psychology, University of Basel, Basel, Switzerland., Geers AL; Department of Psychology, University of Toledo, Toledo, Ohio, USA., Howick J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom., Jensen KB; Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden., Kirsch I; Beth Israel Deaconess Medical Center, Program in Placebo Studies, Boston, Massachusetts, USA., Meissner K; Division of Health Promotion, University of Applied Sciences, Coburg, Germany., Napadow V; Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA., Peerdeman KJ; Health, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, Leiden, the Netherlands., Raz A; Departments of Psychiatry, Neurology and Neurosurgery, McGill University, Montreal, Québec, Canada., Rief W; Department of Clinical Psychology and Psychotherapy, Philipps University of Marburg, Marburg, Germany., Vase L; Department of Psychology and Behavioural Sciences, Aarhus University, Aarhus, Denmark., Wager TD; Department of Psychology and Neuroscience, University of Colorado, Boulder, Colorado, USA., Wampold BE; Department of Counseling Psychology, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Modum Bad Psychiatric Center, Vikersund, Norway., Weimer K; Clinic for Psychosomatic Medicine and Psychotherapy, University Hospital Ulm, Ulm, Germany., Wiech K; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Kaptchuk TJ; Beth Israel Deaconess Medical Center, Program in Placebo Studies, Boston, Massachusetts, USA., Klinger R; Center for Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Kelley JM; Beth Israel Deaconess Medical Center, Program in Placebo Studies, Boston, Massachusetts, USA.
المصدر: Psychotherapy and psychosomatics [Psychother Psychosom] 2018; Vol. 87 (4), pp. 204-210. Date of Electronic Publication: 2018 Jun 12.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Karger Country of Publication: Switzerland NLM ID: 0024046 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0348 (Electronic) Linking ISSN: 00333190 NLM ISO Abbreviation: Psychother Psychosom Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel : Karger
مواضيع طبية MeSH: Consensus* , Evidence-Based Practice* , Nocebo Effect* , Placebo Effect*, Drug-Related Side Effects and Adverse Reactions ; Humans ; Physician-Patient Relations
مستخلص: Background: Placebo and nocebo effects occur in clinical or laboratory medical contexts after administration of an inert treatment or as part of active treatments and are due to psychobiological mechanisms such as expectancies of the patient. Placebo and nocebo studies have evolved from predominantly methodological research into a far-reaching interdisciplinary field that is unravelling the neurobiological, behavioural and clinical underpinnings of these phenomena in a broad variety of medical conditions. As a consequence, there is an increasing demand from health professionals to develop expert recommendations about evidence-based and ethical use of placebo and nocebo effects for clinical practice.
Methods: A survey and interdisciplinary expert meeting by invitation was organized as part of the 1st Society for Interdisciplinary Placebo Studies (SIPS) conference in 2017. Twenty-nine internationally recognized placebo researchers participated.
Results: There was consensus that maximizing placebo effects and minimizing nocebo effects should lead to better treatment outcomes with fewer side effects. Experts particularly agreed on the importance of informing patients about placebo and nocebo effects and training health professionals in patient-clinician communication to maximize placebo and minimize nocebo effects.
Conclusions: The current paper forms a first step towards developing evidence-based and ethical recommendations about the implications of placebo and nocebo research for medical practice, based on the current state of evidence and the consensus of experts. Future research might focus on how to implement these recommendations, including how to optimize conditions for educating patients about placebo and nocebo effects and providing training for the implementation in clinical practice.
(© 2018 S. Karger AG, Basel.)
التعليقات: Comment in: Psychother Psychosom. 2021;90(3):213-214. (PMID: 33631769)
References: Psychopharmacologia. 1965 Jan 14;7(1):57-60. (PMID: 5318924)
Pain. 2001 Feb 15;90(3):205-15. (PMID: 11207392)
N Engl J Med. ;376(14):1387-8. (PMID: 28382806)
Eur Neuropsychopharmacol. 2009 Jan;19(1):34-40. (PMID: 18823760)
Psychother Psychosom. 2017;86(6):332-340. (PMID: 29131050)
Pain. 2016 Dec;157(12):2766-2772. (PMID: 27755279)
N Engl J Med. 2015 Jul 2;373(1):8-9. (PMID: 26132938)
Pain. 2016 Jun;157(6):1179-91. (PMID: 26945235)
Trends Pharmacol Sci. 2012 Mar;33(3):165-72. (PMID: 22284159)
BMJ. 2013 Jul 02;347:f3757. (PMID: 23819963)
Child Care Health Dev. 2008 Jan;34(1):104-10. (PMID: 18171451)
Psychother Psychosom. 2012;81(5):312-4. (PMID: 22854752)
Int Rev Neurobiol. 2018;138:219-240. (PMID: 29681327)
Am J Med. 2015 Feb;128(2):126-9. (PMID: 25232716)
Psychother Psychosom. 2017;86(2):99-107. (PMID: 28183096)
BMJ. 2008 Oct 23;337:a1938. (PMID: 18948346)
PLoS One. 2010 Dec 22;5(12):e15591. (PMID: 21203519)
BMJ. 2008 May 3;336(7651):999-1003. (PMID: 18390493)
Bioethics. 2016 Jul;30(6):407-14. (PMID: 26840547)
Pain. 2014 Aug;155(8):1426-34. (PMID: 24780622)
Exp Dermatol. 2017 Jan;26(1):18-21. (PMID: 27489170)
Kennedy Inst Ethics J. 2016 Mar;26(1):79-103. (PMID: 27157112)
Pain. 2017 Oct;158(10):1893-1902. (PMID: 28614188)
PLoS One. 2013;8(3):e58247. (PMID: 23526969)
JAMA. 2012 Feb 8;307(6):567-8. (PMID: 22318275)
Health Psychol. 2017 Nov;36(11):1074-1082. (PMID: 28277699)
J Evid Based Med. 2017 May;10(2):97-107. (PMID: 28452193)
Nat Rev Drug Discov. 2013 Mar;12(3):191-204. (PMID: 23449306)
BMJ Open. 2017 Jun 30;7(6):e015516. (PMID: 28667217)
J Clin Epidemiol. 2015 Apr;68(4):442-51. (PMID: 25639981)
Pain. 2017 Dec;158(12):2320-2328. (PMID: 28708766)
Pain. 2014 Jun;155(6):1055-8. (PMID: 24333780)
Pharmacol Rev. 2015 Jul;67(3):697-730. (PMID: 26126649)
BMC Med. 2010 Feb 23;8:15. (PMID: 20178561)
Pain. 2016 Aug;157(8):1590-8. (PMID: 27023425)
Anesth Analg. 2010 Mar 1;110(3):868-70. (PMID: 20042440)
Am J Bioeth. 2015;15(10):23-5. (PMID: 26479097)
Nat Rev Neurosci. 2015 Jul;16(7):403-18. (PMID: 26087681)
Pain. 2015 Jan;156(1):39-46. (PMID: 25599299)
Neuroscience. 2015 Oct 29;307:171-90. (PMID: 26272535)
JAMA Psychiatry. 2015 Nov;72(11):1073-4. (PMID: 26421499)
Am J Bioeth. 2017 Jun;17(6):46-48. (PMID: 28537825)
معلومات مُعتمدة: G0800055 United Kingdom MRC_ Medical Research Council
فهرسة مساهمة: Keywords: Clinical practice; Evidence-based ethical recommendations; Nocebo effect; Patient-clinician communication; Patient’s expectancies; Placebo effect
تواريخ الأحداث: Date Created: 20180613 Date Completed: 20181105 Latest Revision: 20220129
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC6191882
DOI: 10.1159/000490354
PMID: 29895014
قاعدة البيانات: MEDLINE
الوصف
تدمد:1423-0348
DOI:10.1159/000490354