دورية أكاديمية
أعرض في EDS

Antiviral Drugs for EBV.

التفاصيل البيبلوغرافية
العنوان: Antiviral Drugs for EBV.
المؤلفون: Pagano JS; Department of Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. joseph_pagano@med.unc.edu., Whitehurst CB; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. cbwhiteh@med.unc.edu., Andrei G; Department of Microbiology and Immunology, University of Leuven, BE-3000 Leuven, Belgium. Graciela.Andrei@rega.kuleuven.be.
المصدر: Cancers [Cancers (Basel)] 2018 Jun 13; Vol. 10 (6). Date of Electronic Publication: 2018 Jun 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI
مستخلص: Epstein⁻Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately 35⁻50% cases when infection occurs during adolescence and early adulthood. Epstein⁻Barr virus is also associated with several B-cell malignancies including Burkitt lymphoma, Hodgkin lymphoma, and post-transplant lymphoproliferative disease. A number of antiviral drugs have proven to be effective inhibitors of EBV replication, yet have resulted in limited success clinically, and none of them has been approved for treatment of EBV infections.
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معلومات مُعتمدة: P01 CA019014 United States CA NCI NIH HHS
فهرسة مساهمة: Keywords: Epstein–Barr virus; acyclovir; antiviral; ganciclovir; maribavir
تواريخ الأحداث: Date Created: 20180615 Latest Revision: 20200930
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC6025560
DOI: 10.3390/cancers10060197
PMID: 29899236
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6694
DOI:10.3390/cancers10060197