دورية أكاديمية
[Impacts of multicomponent environment on intrinsic dissolution rate of berberine in biopharmaceutics classification system of Chinese materia medica].
| العنوان: | [Impacts of multicomponent environment on intrinsic dissolution rate of berberine in biopharmaceutics classification system of Chinese materia medica]. |
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| المؤلفون: | Yin XW; Beijing University of Chinese Medicine, Beijing 100102, China., Wang ZY; Beijing University of Chinese Medicine, Beijing 100102, China., Pan M; Beijing University of Chinese Medicine, Beijing 100102, China., Zhang X; Beijing University of Chinese Medicine, Beijing 100102, China., Wang J; Beijing University of Chinese Medicine, Beijing 100102, China., Li YP; Beijing University of Chinese Medicine, Beijing 100102, China., Dong L; Beijing University of Chinese Medicine, Beijing 100102, China. |
| المصدر: | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2018 Jun; Vol. 43 (11), pp. 2269-2273. |
| نوع المنشور: | Journal Article |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Zhongguo yao xue hui : Zhongguo Zhong yi yan jiu yuan Zhong yao yan jiu suo Country of Publication: China NLM ID: 8913656 Publication Model: Print Cited Medium: Print ISSN: 1001-5302 (Print) Linking ISSN: 10015302 NLM ISO Abbreviation: Zhongguo Zhong Yao Za Zhi Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Beijing : Zhongguo yao xue hui : Zhongguo Zhong yi yan jiu yuan Zhong yao yan jiu suo Original Publication: [Beijing] : Zhongguo yao xue hui : [Zhongguo Zhong yi yan jiu yuan Zhong yao yan jiu suo, 1989- |
| مواضيع طبية MeSH: | Materia Medica*, Berberine/*chemistry , Drugs, Chinese Herbal/*chemistry, Biopharmaceutics ; Solubility |
| مستخلص: | To illustrate the intrinsic dissolution rate(IDR) involved in biopharmaceutics classification system of Chinese materia medica(CMMBCS), investigate the effect of artificial multicomponent environment on IDR of berberine, by using a non-disintegrating disk, and summarize related rules by using the obtained data. Progressive levels design was used to investigate the effects of single component environment (puerarin, baicalin, and glycyrrhizic acid); double-component environment(puerarin+baicalin, puerarin+ glycyrrhizic acid, baicalin+glycyrrhizic acid); and triple-component environment(puerarin+baicalin+glycyrrhizic acid) on IDR of berberine, laying a foundation for further researches on the absorption mechanism of multiple components. Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose. (Copyright© by the Chinese Pharmaceutical Association.) |
| فهرسة مساهمة: | Keywords: berberine; biopharmaceutics classification system of Chinese materia medica; intrinsic dissolution rate |
| المشرفين على المادة: | 0 (Drugs, Chinese Herbal) 0 (Materia Medica) 0I8Y3P32UF (Berberine) |
| تواريخ الأحداث: | Date Created: 20180628 Date Completed: 20190718 Latest Revision: 20190718 |
| رمز التحديث: | 20231215 |
| DOI: | 10.19540/j.cnki.cjcmm.20180322.010 |
| PMID: | 29945378 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1001-5302 |
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| DOI: | 10.19540/j.cnki.cjcmm.20180322.010 |