دورية أكاديمية
LONG TERM OUTCOMES OF AUGMENTED TRABECULECTOMY WITH 5-FLUOROURACIL IN NIGERIA.
العنوان: | LONG TERM OUTCOMES OF AUGMENTED TRABECULECTOMY WITH 5-FLUOROURACIL IN NIGERIA. |
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المؤلفون: | Olawoye OO; Department of Ophthalmology, College of Medicine University of Ibadan, Ibadan, Nigeria., Ashaye AO; Department of Ophthalmology, College of Medicine University of Ibadan, Ibadan, Nigeria. |
المصدر: | Journal of the West African College of Surgeons [J West Afr Coll Surg] 2017 Jan-Mar; Vol. 7 (1), pp. 92-112. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Wolters Kluwer - Medknow Country of Publication: India NLM ID: 101597958 Publication Model: Print Cited Medium: Print ISSN: 2276-6944 (Print) Linking ISSN: 22766944 NLM ISO Abbreviation: J West Afr Coll Surg Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Publication: [Mumbai] : Wolters Kluwer - Medknow Original Publication: Lagos : The West African College of Surgeons, [2011]- |
مستخلص: | Background: Glaucoma in sub-Saharan Africa has been described as a surgical disease because of the high cost of medical treatment, poor compliance and unavailability of medications. Aim: This study reports the long-term outcomes and complication rates following trabeculectomy with 5-fluorouracil in a case series of Nigerians. Design of Study: This was a retrospective, observational, non-comparative case series. Setting: University College Hospital, Ibadan, Nigeria. Methodology: Each patient had complete ophthalmic evaluation. The post-operative intraocular pressure (IOP), visual acuity outcomes and post operative complications were assessed. The World Glaucoma Association consensus on surgical outcome was used to evaluate surgical outcome. Results: Of the 292 patients who presented with glaucoma during this period, a total of 47 eyes of 31 patients (10.6%) had trabeculectomy with 5-FU. The mean presenting intraocular pressure (IOP) was 31.8±12.2mmHg. At three years post-operatively, 48.5% achieved complete success without medications while 90.9% achieved success with or without medications at an IOP cut off of ≤21mmHg. At the same time point of 3 years and an IOP cut off of ≤15mmHg, 63.6% achieved success with or without medications. At a mean post-operative period of 43± 19.6 months, (range 12-86 months), mean IOP had reduced from a preoperative mean of 31.8±12.2mmHg to 15.4±4.7mmHg (P<0.001). Conclusion: Trabeculectomy with 5-Fluorouracil is effective in the long term in reducing IOP with minimal complications in this population of Nigerians. Competing Interests: Competing Interests: The authors have declared that no competing interests exist. |
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فهرسة مساهمة: | Keywords: Nigerians; Surgical Outcome; Trabeculectomy |
تواريخ الأحداث: | Date Created: 20180629 Latest Revision: 20220318 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC6018030 |
PMID: | 29951457 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2276-6944 |
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