دورية أكاديمية
Premaquick © versus modified Bishop score for preinduction cervical assessment at term: A double-blind randomized trial.
| العنوان: | Premaquick © versus modified Bishop score for preinduction cervical assessment at term: A double-blind randomized trial. |
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| المؤلفون: | Eleje GU; Effective Care Research Unit, Department of Obstetrics and Gynecology, Nnamdi Azikiwe University, Awka, Nigeria.; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria., Ezugwu EC; Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria., Ugwu EO; Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria., Ezebialu IU; Department of Obstetrics and Gynecology, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria., Eleje LI; Measurement and Evaluation Unit, Department of Educational Foundations, Nnamdi Azikiwe University, Awka, Nigeria., Ojiegbe NO; Department of Obstetrics and Gynecology, Federal Medical Center, Umuahia, Nigeria., Ajah LO; Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria., Obiora CC; Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Enugu, Nigeria., Egeonu RO; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria., Okafor CG; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria., Enyinna PK; Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Enugu, Nigeria., Egede JO; Department of Obstetrics and Gynecology, Federal Teaching Hospital, Abakaliki, Nigeria., Ugochukwu NJ; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria., Asiegbu AC; Department of Obstetrics and Gynecology, Federal Medical Center, Owerri, Nigeria., Ikechebelu JI; Effective Care Research Unit, Department of Obstetrics and Gynecology, Nnamdi Azikiwe University, Awka, Nigeria.; Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria. |
| المصدر: | The journal of obstetrics and gynaecology research [J Obstet Gynaecol Res] 2018 Aug; Vol. 44 (8), pp. 1404-1414. Date of Electronic Publication: 2018 Jun 28. |
| نوع المنشور: | Journal Article; Multicenter Study; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley on behalf of the Japan Society of Obstetrics and Gynecology] Country of Publication: Australia NLM ID: 9612761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1447-0756 (Electronic) Linking ISSN: 13418076 NLM ISO Abbreviation: J Obstet Gynaecol Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: [Melbourne, Vic. : Wiley on behalf of the Japan Society of Obstetrics and Gynecology] Original Publication: Tokyo : University of Tokyo Press, c1996- |
| مواضيع طبية MeSH: | Cervical Ripening*/drug effects , Outcome Assessment, Health Care*, Labor, Induced/*statistics & numerical data , Obstetrics/*methods , Oxytocics/*therapeutic use , Prostaglandins/*therapeutic use , Uterine Rupture/*epidemiology, Adult ; Biomarkers ; Double-Blind Method ; Female ; Humans ; Nigeria/epidemiology ; Obstetrics/standards ; Pregnancy ; Young Adult |
| مستخلص: | Aim: To test whether Premaquick biomarkers were superior to modified Bishop score for preinduction cervical assessment at term. Methods: A multicenter, double-blind randomized clinical trial in 151 nulliparous, cephalic presenting and singleton pregnancies was conducted. The cervix was considered 'ripe' when at least two out of three Premaquick biomarkers are positive or a Bishop score of ≥6. Main outcome measures were proportion of women who were administered or had additional prostaglandin E1 analogue (PGE1) as a preinduction agent and incidence of uterine rupture. The trial was registered in PACTR registry with approval number PACTR201604001592143. Analysis was performed by intention-to-treat principle. Results: The need for initial PGE1 analogue (77.6% vs 98.7%, risk ratio [RR] =0.47, 95% confidence intervals [95% CI] =0.38-0.59, P < 0.001) and additional PGE1 analogue for cervical ripening after one insertion (44.7% vs 68.0%, RR = 0.63, 95% CI = 0.46-0.86, P = 0.004) was significantly lower in Premaquick group. There was no significant difference in incidence of uterine rupture (0% vs 1.4%, RR = 0.000, P = 0.324); however, the frequency of transition to labor was statistically higher in Premaquick group (44.7% vs 22.7%, RR = 1.59, 95% CI = 1.17-2.15, P = 0.004). Interval from start of induction to any type of delivery, need for oxytocin augmentation, vaginal delivery, number of women with cesarean section for failed induction and number of infants admitted to neonatal intensive care unit were similar between the two groups (P > 0.05). Conclusion: Preinduction cervical assessment with Premaquick was significantly associated with higher frequency of transition to labor and reduced need for PGE1 analogue when compared to modified Bishop score. Further similar trials in other settings are necessary to strengthen or refute this observation. (© 2018 Japan Society of Obstetrics and Gynecology.) |
| فهرسة مساهمة: | Keywords: Premaquick; cervical assessment; induction; labor; modified Bishop score |
| المشرفين على المادة: | 0 (Biomarkers) 0 (Oxytocics) 0 (Prostaglandins) |
| تواريخ الأحداث: | Date Created: 20180630 Date Completed: 20181211 Latest Revision: 20191210 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1111/jog.13691 |
| PMID: | 29956434 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1447-0756 |
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| DOI: | 10.1111/jog.13691 |