دورية أكاديمية
Comparison of Epidural Analgesia Using 0.2% Bupivacaine and 0.2% Ropivacaine for the Management of Postoperative Pain in Major Orthopedic Surgery.
| العنوان: | Comparison of Epidural Analgesia Using 0.2% Bupivacaine and 0.2% Ropivacaine for the Management of Postoperative Pain in Major Orthopedic Surgery. |
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| المؤلفون: | Mehta S; Department of Anaesthesiology, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India., Gajbhare MN; Associate Professor, Department of Anaesthesia, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India., Kamble NP; Assistant Professor, Department of Anaesthesia, B. J. Government Medical College and Sassoon Hospital, Pune, Maharashtra, India. |
| المصدر: | Anesthesia, essays and researches [Anesth Essays Res] 2018 Apr-Jun; Vol. 12 (2), pp. 586-591. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications Country of Publication: India NLM ID: 101578762 Publication Model: Print Cited Medium: Print ISSN: 0259-1162 (Print) Linking ISSN: 22297685 NLM ISO Abbreviation: Anesth Essays Res Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Mumbai] : Medknow Publications |
| مستخلص: | Introduction: Ropivacaine is preferred over racemic bupivacaine for postoperative analgesia as it is less cardiotoxic and has high selectivity for sensory fibers. We aim to compare postoperative epidural analgesia using 0.2% bupivacaine and 0.2% ropivacaine in major lower limb orthopedic surgery. Materials and Methods: In a prospective, randomized, double-blind study, 100 patients, aged 18-70 years, undergoing elective major lower limb orthopedic surgery under spinal anesthesia, were randomly allocated to receive either 7 ml ropivacaine 0.2% (Group R) or 7 ml bupivacaine 0.2% (Group B) for postoperative analgesia through a lumbar epidural catheter. The onset and duration of epidural analgesia, total epidural dose requirement, mean number of epidural topup, rescue analgesia, incidence of motor blockade, and adverse effects were recorded. Results: No differences were noted in demographic data and hemodynamic variables in either group. The onset time of epidural analgesia was 10.46 min ± 0.68 (Group B) and 10.52 min ± 0.71 (Group R). The duration of analgesia was 253.10 ± 17.46 min (Group B) and 251.80 ± 15.77 min (Group R). The total analgesic dose requirement was 78.40 mg ± 6.93 in Group B while in Group R, it was 78.96 mg ± 6.79. Epidural topup requirement and the need for rescue analgesia were similar in both the groups. Motor blockade, hypotension, and nausea were noted more in Group B compared to Group R. Conclusion: In patients undergoing major lower limb orthopedic surgery under subarachnoid block, epidural ropivacaine 0.2% produces effective postoperative analgesia similar to bupivacaine 0.2% with a distinct sensory-motor dissociation resulting in analgesia without motor blockade. Competing Interests: There are no conflicts of interest. |
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| فهرسة مساهمة: | Keywords: Bupivacaine; epidural analgesia; postoperative pain; ropivacaine |
| تواريخ الأحداث: | Date Created: 20180703 Latest Revision: 20220408 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC6020603 |
| DOI: | 10.4103/aer.AER_62_18 |
| PMID: | 29962639 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0259-1162 |
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| DOI: | 10.4103/aer.AER_62_18 |