دورية أكاديمية

Predicting Post-Thrombotic Syndrome with Ultrasonographic Follow-Up after Deep Vein Thrombosis: A Systematic Review and Meta-Analysis.

التفاصيل البيبلوغرافية
العنوان: Predicting Post-Thrombotic Syndrome with Ultrasonographic Follow-Up after Deep Vein Thrombosis: A Systematic Review and Meta-Analysis.
المؤلفون: Dronkers CEA; Department of Medicine - Thrombosis and Hemostasis, Leiden University Medical Center, Leiden University, Leiden, The Netherlands., Mol GC; Department of Internal Medicine, Meander Medical Center, Amersfoort, The Netherlands., Maraziti G; Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy., van de Ree MA; Department of Internal Medicine, Diakonessenhuis Hospital, Utrecht, The Netherlands., Huisman MV; Department of Medicine - Thrombosis and Hemostasis, Leiden University Medical Center, Leiden University, Leiden, The Netherlands., Becattini C; Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy., Klok FA; Department of Medicine - Thrombosis and Hemostasis, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
المصدر: Thrombosis and haemostasis [Thromb Haemost] 2018 Aug; Vol. 118 (8), pp. 1428-1438. Date of Electronic Publication: 2018 Jul 04.
نوع المنشور: Journal Article; Meta-Analysis; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Thieme Country of Publication: Germany NLM ID: 7608063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2567-689X (Electronic) Linking ISSN: 03406245 NLM ISO Abbreviation: Thromb Haemost Subsets: MEDLINE
أسماء مطبوعة: Publication: 2018- : Stuttgart : Thieme
Original Publication: Stuttgart, Schattauer.
مواضيع طبية MeSH: Ultrasonography*, Postthrombotic Syndrome/*etiology , Venous Thrombosis/*complications , Venous Thrombosis/*diagnostic imaging, Aged ; Clinical Decision-Making ; Female ; Humans ; Male ; Middle Aged ; Patient Selection ; Postthrombotic Syndrome/prevention & control ; Predictive Value of Tests ; Prognosis ; Reproducibility of Results ; Risk Assessment ; Risk Factors ; Stockings, Compression ; Time Factors ; Venous Thrombosis/therapy
مستخلص: Background:  Post-thrombotic syndrome (PTS) is a common and potential severe complication of deep venous thrombosis (DVT). Elastic compression stocking therapy may prevent PTS if worn on a daily basis, but stockings are cumbersome to apply and uncomfortable to wear. Hence, identification of predictors of PTS may help physicians to select patients at high risk of PTS.
Aims:  This article identifies ultrasonography (US) parameters assessed during or after treatment of DVT of the leg, that predict PTS.
Methods:  This is a systematic review and meta-analysis study. Databases were searched for prospective studies including consecutive patients with DVT who received standardized treatment, had an US during follow-up assessing findings consistent with vascular damage after DVT and had a follow-up period of at least 6 months for the occurrence of PTS assessed by a standardized protocol.
Results:  The literature search revealed 1,156 studies of which 1,068 were irrelevant after title and abstract screening by three independent reviewers. After full-text screening, 12 relevant studies were included, with a total of 2,684 analysed patients. Two US parameters proved to be predictive of PTS: residual vein thrombosis, for a pooled odds ratio (OR) of 2.17 (95% confidence interval [CI], 1.79-2.63) and venous reflux at the popliteal level, for a pooled OR of 1.34 (95% CI, 1.03-1.75).
Conclusion:  The US features reflux and residual thrombosis measured at least 6 weeks after DVT predict PTS. Whether these features may be used to identify patients who may benefit from compression therapy remains to be assessed in further studies.
Competing Interests: None.
(Georg Thieme Verlag KG Stuttgart · New York.)
تواريخ الأحداث: Date Created: 20180705 Date Completed: 20190924 Latest Revision: 20190925
رمز التحديث: 20240628
DOI: 10.1055/s-0038-1666859
PMID: 29972864
قاعدة البيانات: MEDLINE
الوصف
تدمد:2567-689X
DOI:10.1055/s-0038-1666859