دورية أكاديمية

Should splenic autotransplantation be considered after total splenectomy due to trauma?

التفاصيل البيبلوغرافية
العنوان: Should splenic autotransplantation be considered after total splenectomy due to trauma?
المؤلفون: Cardoso DL; - University of Fortaleza, Faculty of Medicine, Fortaleza, CE, Brazil., Cardoso Filho FA; - General Hospital of Fortaleza, General Surgery, Fortaleza, Ceará, Brazil., Cardoso AL; - Christus University (Unichristus), Faculty of Medicine, Fortaleza, Ceará, Brazil., Gonzaga ML; - Federal University of Ceará, Faculty of Medicine, Fortaleza, CE, Brazil., Grande AJ; - State University of Mato Grosso do Sul, Faculty of Medicine, Dourados, MS, Brazil.
المصدر: Revista do Colegio Brasileiro de Cirurgioes [Rev Col Bras Cir] 2018 Jul 10; Vol. 45 (3), pp. e1850. Date of Electronic Publication: 2018 Jul 10.
نوع المنشور: Journal Article; Review
اللغة: English; Portuguese
بيانات الدورية: Publisher: Colégio Brasileiro de Cirurgiões Country of Publication: Brazil NLM ID: 7809515 Publication Model: Electronic Cited Medium: Internet ISSN: 1809-4546 (Electronic) Linking ISSN: 01006991 NLM ISO Abbreviation: Rev Col Bras Cir Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Rio de Janeiro : Colégio Brasileiro de Cirurgiões, [1974?]-
مواضيع طبية MeSH: Postoperative Complications/*prevention & control , Spleen/*injuries , Spleen/*transplantation , Splenectomy/*adverse effects, Humans ; Infections/etiology ; Medical Illustration ; Risk Factors ; Splenectomy/methods ; Transplantation, Autologous
مستخلص: Trauma is a public health problem and the most common cause of death in people under the age of 45. In blunt abdominal trauma, the spleen is the most commonly injured organ. Splenectomy remains the most common treatment, especially in high-grade lesions, despite increased nonoperative treatment. Removal of the spleen leads to increased susceptibility to infections due to its role in the immune function. Postsplenectomy sepsis is an important complication and presents a high mortality rate. Patients undergoing splenectomy should be immunized for encapsulated germs, as these are the agents most commonly associated with such infections. Splenic autotransplantation is a simple procedure, which can be an alternative to reduce infection rates consequent to total splenectomy, and reduce costs related to hospitalizations. This review aims to provide evidence-based information on splenic autotransplantation and its impact on the prognosis of patients undergoing total splenectomy. We searched the Cochrane Library, Medline/PubMed, SciELO and Embase, from January 2017 to January 2018 and selected articles in English and Portuguese, dated from 1919 to 2017. We found that the adjusted risk of death in splenectomized patients is greater than that of the general population, and when total splenectomy is performed, splenic autotransplantation is the only method capable of preserving splenic function, avoiding infections, especially postsplenectomy sepsis. Health professionals should be familiar with the consequences of the method chosen to manage the patient suffering from splenic trauma.
تواريخ الأحداث: Date Created: 20180712 Date Completed: 20190605 Latest Revision: 20240327
رمز التحديث: 20240327
DOI: 10.1590/0100-6991e-20181850
PMID: 29995152
قاعدة البيانات: MEDLINE
الوصف
تدمد:1809-4546
DOI:10.1590/0100-6991e-20181850