دورية أكاديمية
أعرض في EDS

Kaposi's sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital.

التفاصيل البيبلوغرافية
العنوان: Kaposi's sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital.
المؤلفون: Pires CAA; Department of Clinical Medicine, Universidade Federal do Pará, Belém (PA), Brazil.; Department of Dermatology, Universidade do Estado do Pará, Belém (PA), Brazil., Noronha MAN; Medical student, Universidade Federal do Pará, Belém (PA), Brazil., Monteiro JCMS; Department of Clinical Medicine, Hospital Universitário João de Barros Barreto, Universidade Federal do Pará, Belém (PA), Brazil., Costa ALCD; Department of Family and Community Medicine, Centro Universitário do Pará, Belém (PA), Brazil., Abreu Júnior JMC; Pathology Department, Hospital Universitário João de Barros Barreto, Universidade Federal do Pará, Belém (PA), Brazil.
المصدر: Anais brasileiros de dermatologia [An Bras Dermatol] 2018 Jul-Aug; Vol. 93 (4), pp. 524-528.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier España, S.L Country of Publication: Spain NLM ID: 0067662 Publication Model: Print Cited Medium: Internet ISSN: 1806-4841 (Electronic) Linking ISSN: 03650596 NLM ISO Abbreviation: An Bras Dermatol Subsets: MEDLINE
أسماء مطبوعة: Publication: Barcelona, Spain : Elsevier España, S.L.
Original Publication: Rio De Janeiro : Sociedade Brasileira de Dermatologia
مواضيع طبية MeSH: AIDS-Related Opportunistic Infections/*epidemiology , Sarcoma, Kaposi/*epidemiology, AIDS-Related Opportunistic Infections/drug therapy ; AIDS-Related Opportunistic Infections/pathology ; Adolescent ; Adult ; Antiretroviral Therapy, Highly Active ; Brazil/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sarcoma, Kaposi/drug therapy ; Sarcoma, Kaposi/pathology ; Socioeconomic Factors ; Tertiary Care Centers ; Young Adult
مستخلص: Background: Kaposi's sarcoma (KS) is a rare neoplasm with indolent progression. Since 1981, the Kaposi's sarcoma epidemic has increased as co-infection with HIV.
Objectives: The study aimed to identify the clinical and demographic characteristics and therapeutic approaches in HIV/AIDS patients in a regional referral hospital.
Methods: We analyzed the medical records of 51 patients with histopathological diagnosis of Kaposi's sarcoma hospitalized at Hospital Universitário João de Barros Barreto (HUJBB) from 2004 to 2015.
Results: The study sample consisted of individuals 15 to 44 years of age (80.4%), male (80.4%), single (86.3%), and residing in Greater Metropolitan Belém, Pará State, Brazil. The primary skin lesions identified at diagnosis were violaceous macules (45%) and violaceous papules (25%). Visceral involvement was seen in 62.7%, mainly affecting the stomach (75%). The most frequent treatment regimen was 2 NRTI + NNRTI, and 60.8% were referred to chemotherapy.
Study Limitations: We assumed that more patients had been admitted to hospital without histopathological confirmation or with pathology reports from other services, so that the current study probably underestimated the number of KS cases.
Conclusion: Although the cutaneous manifestations in most of these patients were non-exuberant skin lesions like macules and papules, many already showed visceral involvement. Meticulous screening of these patients is thus mandatory, even if the skin lesions are subtle and localized.
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SCR Disease Name: AIDS-related Kaposi sarcoma
تواريخ الأحداث: Date Created: 20180802 Date Completed: 20180910 Latest Revision: 20240229
رمز التحديث: 20240229
مُعرف محوري في PubMed: PMC6063130
DOI: 10.1590/abd1806-4841.20186978
PMID: 30066758
قاعدة البيانات: MEDLINE
الوصف
تدمد:1806-4841
DOI:10.1590/abd1806-4841.20186978