التفاصيل البيبلوغرافية
| العنوان: |
THE ROLE OF THE TRANSDIAPHRAGMATIC PRESSURE GRADIENT IN THE PATHOPHYSIOLOGY OF GASTROESOPHAGEAL REFLUX DISEASE. |
| المؤلفون: |
Del Grande LM; Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Cirurgia, São Paulo, SP, Brasil., Herbella FAM; Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Cirurgia, São Paulo, SP, Brasil., Katayama RC; Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Cirurgia, São Paulo, SP, Brasil., Schlottmann F; University of North Carolina, Department of Medicine and Surgery, Chapel Hill, North Carolina, USA., Patti MG; University of North Carolina, Department of Medicine and Surgery, Chapel Hill, North Carolina, USA. |
| المصدر: |
Arquivos de gastroenterologia [Arq Gastroenterol] 2018 Nov; Vol. 55Suppl 1 (Suppl 1), pp. 13-17. Date of Electronic Publication: 2018 Aug 06. |
| نوع المنشور: |
Journal Article; Review |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia Country of Publication: Brazil NLM ID: 15310600R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4219 (Electronic) Linking ISSN: 00042803 NLM ISO Abbreviation: Arq Gastroenterol Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: São Paulo, Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia. |
| مواضيع طبية MeSH: |
Esophageal Sphincter, Lower/*physiopathology , Esophagogastric Junction/*physiopathology , Gastroesophageal Reflux/*physiopathology, Gastroesophageal Reflux/etiology ; Humans ; Lung Diseases/complications ; Lung Diseases/physiopathology ; Manometry ; Obesity/complications ; Obesity/physiopathology ; Risk Factors |
| مستخلص: |
Gastroesophageal reflux disease (GERD) is the most common disease of the upper gastrointestinal tract in the Western world. GERD pathophysiology is multifactorial. Different mechanisms may contribute to GERD including an increase in the transdiaphragmatic pressure gradient (TPG). The pathophysiology of GERD linked to TPG is not entirely understood. This review shows that TPG is an important contributor to GERD even when an intact esophagogastric barrier is present in the setting of obesity and pulmonary diseases. |
| تواريخ الأحداث: |
Date Created: 20180809 Date Completed: 20190206 Latest Revision: 20190215 |
| رمز التحديث: |
20221213 |
| DOI: |
10.1590/S0004-2803.201800000-39 |
| PMID: |
30088531 |
| قاعدة البيانات: |
MEDLINE |
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