دورية أكاديمية
Nucleus of the Solitary Tract Serotonin 5-HT 2C Receptors Modulate Food Intake.
العنوان: | Nucleus of the Solitary Tract Serotonin 5-HT |
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المؤلفون: | D'Agostino G; Rowett Institute, University of Aberdeen, Aberdeen, UK; Department of Pharmacology, University of Cambridge, Cambridge, UK. Electronic address: giuseppe.dagostino@abdn.ac.uk., Lyons D; Rowett Institute, University of Aberdeen, Aberdeen, UK., Cristiano C; Rowett Institute, University of Aberdeen, Aberdeen, UK., Lettieri M; Rowett Institute, University of Aberdeen, Aberdeen, UK., Olarte-Sanchez C; Rowett Institute, University of Aberdeen, Aberdeen, UK., Burke LK; Department of Pharmacology, University of Cambridge, Cambridge, UK., Greenwald-Yarnell M; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Cansell C; Rowett Institute, University of Aberdeen, Aberdeen, UK., Doslikova B; Department of Pharmacology, University of Cambridge, Cambridge, UK., Georgescu T; Rowett Institute, University of Aberdeen, Aberdeen, UK., Martinez de Morentin PB; Rowett Institute, University of Aberdeen, Aberdeen, UK., Myers MG Jr; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Rochford JJ; Rowett Institute, University of Aberdeen, Aberdeen, UK., Heisler LK; Rowett Institute, University of Aberdeen, Aberdeen, UK; Department of Pharmacology, University of Cambridge, Cambridge, UK. Electronic address: lora.heisler@abdn.ac.uk. |
المصدر: | Cell metabolism [Cell Metab] 2018 Oct 02; Vol. 28 (4), pp. 619-630.e5. Date of Electronic Publication: 2018 Aug 23. |
نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Cambridge, Mass. : Cell Press, c2005- |
مواضيع طبية MeSH: | Appetite Depressants/*therapeutic use , Benzazepines/*therapeutic use , Eating/*physiology , Obesity/*drug therapy , Serotonin 5-HT2 Receptor Agonists/*therapeutic use , Solitary Nucleus/*metabolism, Analysis of Variance ; Animals ; Appetite Depressants/metabolism ; Appetite Regulation/drug effects ; Arcuate Nucleus of Hypothalamus/cytology ; Benzazepines/metabolism ; Cell Line, Tumor ; Feeding Behavior/physiology ; Male ; Mice ; Mice, Knockout ; Neurons/metabolism ; Receptor, Serotonin, 5-HT2C/metabolism ; Serotonin 5-HT2 Receptor Agonists/metabolism ; Statistics, Nonparametric ; Transfection |
مستخلص: | To meet the challenge to human health posed by obesity, a better understanding of the regulation of feeding is essential. Medications targeting 5-hydroxytryptamine (5-HT; serotonin) 2C receptors (htr2c; 5-HT (Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.) |
التعليقات: | Comment in: Cell Metab. 2018 Oct 2;28(4):533-534. (PMID: 30282043) |
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معلومات مُعتمدة: | MC/PC/15077 United Kingdom MRC_ Medical Research Council; WT098012 United Kingdom WT_ Wellcome Trust; P30 DK034933 United States DK NIDDK NIH HHS; MR/P009824/1 United Kingdom MRC_ Medical Research Council; BB/K001418/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/K017772/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; R01 DK056731 United States DK NIDDK NIH HHS; 105625/Z/14/Z United Kingdom WT_ Wellcome Trust; MR/L002620/1 United Kingdom MRC_ Medical Research Council; BB/N017838/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; R37 DK056731 United States DK NIDDK NIH HHS; P30 DK020572 United States DK NIDDK NIH HHS; MC_PC_15077 United Kingdom MRC_ Medical Research Council; United Kingdom WT_ Wellcome Trust |
فهرسة مساهمة: | Keywords: 5-HT(2C)R; food intake; lorcaserin; nucleus of the solitary tract; obesity; serotonin |
المشرفين على المادة: | 0 (Appetite Depressants) 0 (Benzazepines) 0 (Receptor, Serotonin, 5-HT2C) 0 (Serotonin 5-HT2 Receptor Agonists) 637E494O0Z (lorcaserin) |
تواريخ الأحداث: | Date Created: 20180828 Date Completed: 20191021 Latest Revision: 20220129 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC6371983 |
DOI: | 10.1016/j.cmet.2018.07.017 |
PMID: | 30146485 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1932-7420 |
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DOI: | 10.1016/j.cmet.2018.07.017 |