دورية أكاديمية

Cerebrospinal Fluid Leak and Symptomatic Pseudomeningocele After Intradural Spine Surgery.

التفاصيل البيبلوغرافية
العنوان: Cerebrospinal Fluid Leak and Symptomatic Pseudomeningocele After Intradural Spine Surgery.
المؤلفون: Sellin JN; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA., Kolcun JPG; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA., Levi AD; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address: ALevi@med.miami.edu.
المصدر: World neurosurgery [World Neurosurg] 2018 Dec; Vol. 120, pp. e497-e502. Date of Electronic Publication: 2018 Aug 24.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101528275 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-8769 (Electronic) Linking ISSN: 18788750 NLM ISO Abbreviation: World Neurosurg Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York : Elsevier
مواضيع طبية MeSH: Cerebrospinal Fluid Leak/*etiology , Meningocele/*etiology , Postoperative Complications/*surgery , Postoperative Complications/*therapy , Spine/*surgery, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cerebrospinal Fluid Leak/therapy ; Drainage ; Dura Mater/surgery ; Female ; Humans ; Intraoperative Care ; Male ; Meningocele/therapy ; Middle Aged ; Neurosurgical Procedures/methods ; Postoperative Care ; Retrospective Studies ; Risk Factors ; Young Adult
مستخلص: Objective: To describe the incidence of and characterize risk factors for cerebrospinal fluid leak and symptomatic pseudomeningocele (CSFL/SP) after intradural spine surgery.
Methods: A retrospective analysis of a prospectively collected and consecutive series of patients undergoing intradural spine surgery by the senior author (A.D.L.) was conducted over a period of 20 years.
Results: Data on 460 surgeries performed on 430 consecutive patients were gathered. The incidence of CSFL/SP formation was 2.8% (n = 13). Of the 13 cases complicated by CSFL/SP, 4 were successfully managed nonoperatively (4/13, 31%); 9 postoperative CSFL/SP required surgical repair (9/13, 69%), making for an overall postoperative surgical repair rate of 1.9% (9/460). Factors significantly related to development of postoperative CSFL/SP on the Fisher exact test were surgery located at the craniocervical junction (risk ratio [RR] 2.7, P = 0.03) and use of any external cerebrospinal fluid drain (any drain: RR 2.5, P = 0.02; lumbar drain specifically: RR 2.6, P = 0.02), the latter finding most likely being attributable to selection bias. No significant difference was observed between primary dural closure and closure incorporating the use of one or more dural repair adjuncts. In addition, the total number of dural repair adjuncts used did not significantly influence the development of postoperative CSFL/SP.
Conclusions: We present the largest series of intradural spine surgeries focusing specifically on the risk factors for and management of CSFL/SP. Although craniocervical junction surgery and use of external cerebrospinal fluid drain were associated with CSFL/SP, type of closure and type/number of dural substitutes were not.
(Copyright © 2018 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Cerebrospinal fluid leak; Intradural spine surgery; Symptomatic pseudomeningocele
تواريخ الأحداث: Date Created: 20180828 Date Completed: 20181217 Latest Revision: 20181217
رمز التحديث: 20240628
DOI: 10.1016/j.wneu.2018.08.112
PMID: 30149160
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-8769
DOI:10.1016/j.wneu.2018.08.112