دورية أكاديمية
أعرض في EDS

Thresholds in the Relationship of Quadriceps Strength With Functional Limitations in Women With Knee Osteoarthritis.

التفاصيل البيبلوغرافية
العنوان: Thresholds in the Relationship of Quadriceps Strength With Functional Limitations in Women With Knee Osteoarthritis.
المؤلفون: Bacon KL; Boston University, Boston, Massachusetts., Segal NA; University of Kansas, Kansas City., Øiestad BE; Oslo Metropolitan University, Oslo, Norway., Lewis CE; University of Alabama, Birmingham., Nevitt MC; University of California, San Francisco., Brown C; Boston University School of Medicine, Boston, Massachusetts., LaValley MP; Boston University, Boston, Massachusetts., McCulloch CE; University of California, San Francisco., Felson DT; Boston University, Boston, Massachusetts, NIHR Manchester Musculoskeletal Biomedical Research Centre, Manchester University NHS Foundation Trust, and Manchester Academic Health Science Centre, Manchester, UK.
المصدر: Arthritis care & research [Arthritis Care Res (Hoboken)] 2019 Sep; Vol. 71 (9), pp. 1186-1193. Date of Electronic Publication: 2019 Aug 06.
نوع المنشور: Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101518086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2151-4658 (Electronic) Linking ISSN: 2151464X NLM ISO Abbreviation: Arthritis Care Res (Hoboken) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hoboken, NJ : John Wiley & Sons
مواضيع طبية MeSH: Activities of Daily Living* , Disability Evaluation*, Muscle Strength/*physiology , Osteoarthritis, Knee/*diagnosis , Quadriceps Muscle/*physiopathology , Range of Motion, Articular/*physiology, Aged ; Anaerobic Threshold ; Body Mass Index ; Cohort Studies ; Female ; Humans ; Iowa ; Linear Models ; Logistic Models ; Middle Aged ; Osteoarthritis, Knee/epidemiology ; Physical Examination/methods ; Prognosis ; Prospective Studies ; Risk Assessment ; Severity of Illness Index ; Walk Test
مستخلص: Objective: To investigate thresholds of strength below which individuals with knee osteoarthritis (OA) may have more difficulty carrying out physical functions of daily life. Individuals below such thresholds might benefit more from strengthening interventions than those with greater strength.
Methods: We studied individuals with symptomatic OA at baseline in the Multicenter Osteoarthritis Study who had knee extensor strength measured isokinetically at 60º/second. Participants underwent a 20-meter walk test and a sit-to-stand test and answered questions from the Western Ontario and McMaster Universities Osteoarthritis Index. Physical function results were plotted against measures of quadriceps strength (Nm) (and as strength:body weight) for the worst knee. Loess technique was used to examine inflection points. Nonlinear relationships were examined in piecewise linear regression models. Differences were tested using linear and logistic regression models.
Results: The study had 834 participants (65.8% women). The mean ± SD age of the participants was 62.9 ± 7.9 years. In women, there were thresholds of strength below which the slope of strength versus function was steeper: walking speed (<58 Nm), chair stand time (<32 Nm), and the McMaster Universities Osteoarthritis Index functions of rising from a chair and getting on/off the toilet (<38 Nm). We found no thresholds in men. Loess analyses using strength:weight showed similar results.
Conclusion: In individuals with symptomatic knee OA, thresholds in the strength function relationship may help identify individuals, especially women, at the brink of disability insofar as strength and capacity for daily tasks. In those with low strength, small increments in strength may be associated with improvement in function and greater ease with common daily life, emphasizing the importance of preventing loss of strength.
(© 2018, American College of Rheumatology.)
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معلومات مُعتمدة: U01 AG018947 United States AG NIA NIH HHS; P60 AR047785 United States AR NIAMS NIH HHS; U01 AG018832 United States AG NIA NIH HHS; P30 AR072571 United States AR NIAMS NIH HHS; R01 NS048597 United States NS NINDS NIH HHS; T32 AR007598 United States AR NIAMS NIH HHS; U01 AG019069 United States AG NIA NIH HHS; U01 AG018820 United States AG NIA NIH HHS
تواريخ الأحداث: Date Created: 20180830 Date Completed: 20200317 Latest Revision: 20230721
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC6395532
DOI: 10.1002/acr.23740
PMID: 30156759
قاعدة البيانات: MEDLINE
الوصف
تدمد:2151-4658
DOI:10.1002/acr.23740