تقرير
Chronic genotype 1 hepatitis E infection from immunosuppression for ileo-colonic Crohn's disease.
| العنوان: | Chronic genotype 1 hepatitis E infection from immunosuppression for ileo-colonic Crohn's disease. |
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| المؤلفون: | Robins AEM; Department of Hepatology, University Hospitals of Cambridge, Addenbrookes Hospital, Hills Rd, Cambridge CB2 0QQ, UK., Bowden DJ; Department of Radiology, University Hospitals of Cambridge, Addenbrookes Hospital, Hills Rd, Cambridge CB2 0QQ, UK., Gelson WTH; Department of Hepatology, University Hospitals of Cambridge, Addenbrookes Hospital, Hills Rd, Cambridge CB2 0QQ, UK. |
| المصدر: | Oxford medical case reports [Oxf Med Case Reports] 2018 Aug 25; Vol. 2018 (9), pp. omy059. Date of Electronic Publication: 2018 Aug 25 (Print Publication: 2018). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Published by Oxford University Press and JSCR Publishing Ltd Country of Publication: England NLM ID: 101642070 Publication Model: eCollection Cited Medium: Print ISSN: 2053-8855 (Print) Linking ISSN: 20538855 NLM ISO Abbreviation: Oxf Med Case Reports Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Oxford, UK] : Published by Oxford University Press and JSCR Publishing Ltd., [2014] |
| مستخلص: | We report a case of a 33-year-old man with a background of longstanding ileo-colonic Crohn's disease and primary sclerosing cholangitis. Following a trip to India he developed diarrhoea which was treated as an exacerbation of Crohn's disease. Liver tests became chronically deranged after increasing immunosuppression, which comprised mercaptopurine, adalimumab and prednisolone. Chronic genotype 1 hepatitis E was diagnosed and successfully treated with reduction of immunosuppression followed by a 24-week course of ribavirin. We believe that this is the first reported case of chronic hepatitis E in genotype 1. Deranged liver tests should prompt testing for hepatitis E infection in the context of immunosuppression for inflammatory bowel disease. |
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| تواريخ الأحداث: | Date Created: 20180831 Latest Revision: 20231103 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC6109198 |
| DOI: | 10.1093/omcr/omy059 |
| PMID: | 30159153 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2053-8855 |
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| DOI: | 10.1093/omcr/omy059 |