دورية أكاديمية
أعرض في EDS

The Antibacterial Effect of Two Cavity Disinfectants against One of Cariogenic Pathogen: An In vitro Comparative Study.

التفاصيل البيبلوغرافية
العنوان: The Antibacterial Effect of Two Cavity Disinfectants against One of Cariogenic Pathogen: An In vitro Comparative Study.
المؤلفون: Elgamily HM; Restorative and Dental Materials Department, Oral and Dental Research Division, National Research Centre, Giza, Egypt., El-Sayed HS; Department of Dairy Science, Food Industries and Nutrition Division, National Research Centre, Giza, Egypt., Abdelnabi A; Restorative and Dental Materials Department, Oral and Dental Research Division, National Research Centre, Giza, Egypt.
المصدر: Contemporary clinical dentistry [Contemp Clin Dent] 2018 Jul-Sep; Vol. 9 (3), pp. 457-462.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Medknow Publications and Media Pvt. Ltd Country of Publication: India NLM ID: 101552967 Publication Model: Print Cited Medium: Print ISSN: 0976-237X (Print) Linking ISSN: 09762361 NLM ISO Abbreviation: Contemp Clin Dent Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Mumbai : Medknow Publications and Media Pvt. Ltd.
مستخلص: Introduction: Bacteria residing in the oral cavity penetrate freely through the resultant fissures under the fillings, which might lead to the development of secondary caries. Nowadays dentistry, different nanotechnological materials with antibacterial activity are being developed for oral cavity disinfection.
Aim: This study aims to investigate the antibacterial activity of a new cavity disinfectant NanoCare Plus Silver Gold ® (NanoCare) in comparison to (0.2%) chlorhexidine (CHX) gluconate disinfectant against Streptococcus mutans growth and colony count using Agar well diffusion method and contact test, respectively, and also, to assess the nanoparticles (NPs) size distribution and Zeta potential of a NanoCare disinfectant.
Materials and Methods: A total of 36 samples of cavity disinfectants were divided into two main groups (G) ( n = 18); G1: NanoCare, and G2: CHX. Each group was subdivided into two subgroups (C) ( n = 9) according to the antimicrobial test that the samples were subjected to.
Results: A chlorohexidine group demonstrated the higher mean inhibition zone values than NanoCare group where P ≤ 0.05, as well both groups had a significant decrease in bacterial colony count where P ≤ 0.001. The particles size distribution in NanoCare sample was found that 99% of particles number with an average size of 29.07 nm and 1% was 136.7 nm, while the Zeta potential value was -6.5 mV.
Conclusions: NanoCare cavity disinfectant displayed good antibacterial property against S. mutans . The innovative incorporation of NPs into this cavity disinfectant could be used to improve the antimicrobial capacity of the material and help to decrease secondary caries risk.
Competing Interests: There are no conflicts of interest.
References: Quintessence Int. 2009 Feb;40(2):155-61. (PMID: 19365897)
Physiol Behav. 2001 Sep 1-15;74(1-2):85-99. (PMID: 11564456)
Eur J Dent. 2014 Apr;8(2):184-90. (PMID: 24966768)
J Endod. 2010 Jun;36(6):1030-5. (PMID: 20478460)
J Conserv Dent. 2009 Jul;12(3):109-13. (PMID: 20543917)
Small. 2011 May 23;7(10):1322-37. (PMID: 21520409)
J Dent Res. 2010 Nov;89(11):1175-86. (PMID: 20739694)
Braz Dent J. 2014;25(2):141-5. (PMID: 25140719)
Acta Biomater Odontol Scand. 2015 Sep 18;1(2-4):51-58. (PMID: 28642901)
Small. 2008 Jan;4(1):26-49. (PMID: 18165959)
Restor Dent Endod. 2013 Feb;38(1):36-42. (PMID: 23493656)
Dent Mater J. 2016;35(1):147-52. (PMID: 26830836)
J Biomed Mater Res A. 2016 Jan;104(1):209-17. (PMID: 26282184)
J Endod. 1999 Mar;25(3):167-71. (PMID: 10321180)
Aust Endod J. 2006 Dec;32(3):112-5. (PMID: 17201752)
Quintessence Int. 2011 Mar;42(3):213-23. (PMID: 21465008)
J Nanobiotechnology. 2015 Jan 16;13:1. (PMID: 25592092)
Clin Oral Investig. 2014 Apr;18(3):819-27. (PMID: 23873326)
Nano Today. 2011 Dec;6(6):585-607. (PMID: 23293661)
Odontology. 2006 Sep;94(1):1-9. (PMID: 16998612)
J Clin Periodontol. 2010 Nov;37(11):988-97. (PMID: 20738456)
Methods Mol Biol. 2010;610:123-44. (PMID: 20013176)
Adv Drug Deliv Rev. 2013 Nov;65(13-14):1803-15. (PMID: 23892192)
Acta Bioeng Biomech. 2016;18(2):59-70. (PMID: 27405339)
J Dent Res. 2015 Aug;94(8):1085-91. (PMID: 26040283)
Adv Appl Microbiol. 2009;69:99-132. (PMID: 19729092)
Dalton Trans. 2012 Jun 7;41(21):6507-15. (PMID: 22411188)
J Biomed Res. 2012 May;26(3):143-51. (PMID: 23554743)
فهرسة مساهمة: Keywords: Antibacterial effect; Streptococcus mutans; cavity disinfectant; chlorhexidine; gold nanoparticles; silver nanoparticles
تواريخ الأحداث: Date Created: 20180901 Latest Revision: 20220321
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC6104352
DOI: 10.4103/ccd.ccd_308_18
PMID: 30166844
قاعدة البيانات: MEDLINE
الوصف
تدمد:0976-237X
DOI:10.4103/ccd.ccd_308_18