دورية أكاديمية
Technological development of microemulsions with perspectives for pain treatment: a patent review.
| العنوان: | Technological development of microemulsions with perspectives for pain treatment: a patent review. |
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| المؤلفون: | Lima MPD; a Medicinal Plants Research nucleus, Center of Health Sciences , Federal University of Piauí , Teresina , Brazil., Lopes EM; a Medicinal Plants Research nucleus, Center of Health Sciences , Federal University of Piauí , Teresina , Brazil., Gomes LDS; a Medicinal Plants Research nucleus, Center of Health Sciences , Federal University of Piauí , Teresina , Brazil., França ARS; a Medicinal Plants Research nucleus, Center of Health Sciences , Federal University of Piauí , Teresina , Brazil., Acha BT; a Medicinal Plants Research nucleus, Center of Health Sciences , Federal University of Piauí , Teresina , Brazil., Carvalho ALM; b Department of Pharmacy, Center of Health Sciences , Federal University of Piauí , Teresina , Brazil., Almeida FRC; a Medicinal Plants Research nucleus, Center of Health Sciences , Federal University of Piauí , Teresina , Brazil. |
| المصدر: | Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2018 Sep; Vol. 28 (9), pp. 691-702. Date of Electronic Publication: 2018 Sep 14. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: London : Ashley Pub. Ltd., c1994- |
| مواضيع طبية MeSH: | Drug Delivery Systems* , Drug Design*, Pain/*drug therapy, Administration, Cutaneous ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Biotechnology ; Emulsions ; Humans ; Oils, Volatile/chemistry ; Patents as Topic ; Thermodynamics |
| مستخلص: | Introduction: Microemulsions are thermodynamically stable translucent systems widely used for systemic delivery of drugs. The present study is the first to analyze the biotechnological potential of microemulsion systems for therapeutic purposes, through transdermal route, for pain treatment. Areas Covered: Patents were searched in the World Intellectual Property Organization (WIPO), European Patent Office (Espacenet), United States Patent and Trademark Office (USPTO) and National Institute of Intellectual Property (INPI). The inclusion criteria were published patents containing the keywords; 'microemulsion' and 'transdermal' in their title or abstract. 208 patents were found. However, only those patents which mentioned in their abstract or in their description the use of microemulsion system (object of invention) for pain treatment were selected. Were excluded duplicate patents and those that did not report pharmacological use of MEs specifically for pain treatment. Thus, sixteen patents were selected and described in the present study. Expert Opinion: Patents were found that focused specifically on the development process of microemulsion systems, the inclusion of essential oils in microemulsions, which place microemulsions as delivery systems for NSAIDs and other substances, as well as microemulsions for transdermal administration. These studies reinforce the therapeutic applicability of MEs in the treatment of acute and chronic pain. |
| فهرسة مساهمة: | Keywords: Microemulsion; biotechnology; pain treatment; patents; technological prospect |
| المشرفين على المادة: | 0 (Anti-Inflammatory Agents, Non-Steroidal) 0 (Emulsions) 0 (Oils, Volatile) |
| تواريخ الأحداث: | Date Created: 20180904 Date Completed: 20181018 Latest Revision: 20190222 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/13543776.2018.1519025 |
| PMID: | 30175633 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1744-7674 |
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| DOI: | 10.1080/13543776.2018.1519025 |