دورية أكاديمية
أعرض في EDS

Seroprevalence of hepatitis B virus infection and associated factors among healthcare workers in northern Tanzania.

التفاصيل البيبلوغرافية
العنوان: Seroprevalence of hepatitis B virus infection and associated factors among healthcare workers in northern Tanzania.
المؤلفون: Shao ER; Internal Medicine Department, Kilimanjaro Christian Medical Center, P.O.Box3010, Moshi, United Republic of Tanzania. elichilia2004@yahoo.co.uk.; Institute of Public Health, Community Health Department, Kilimanjaro Christian Medical University College, P.O.Box2240, Moshi, Tanzania. elichilia2004@yahoo.co.uk.; Better Human Health Foundation, P.O.Box1348, Moshi, Tanzania. elichilia2004@yahoo.co.uk.; Imagedoctors International, P.O.Box16341, Arusha, Tanzania. elichilia2004@yahoo.co.uk., Mboya IB; Institute of Public Health, Community Health Department, Kilimanjaro Christian Medical University College, P.O.Box2240, Moshi, Tanzania., Gunda DW; CUHAS, P.O.Box 1370, Mwanza, Tanzania., Ruhangisa FG; Internal Medicine Department, Kilimanjaro Christian Medical Center, P.O.Box3010, Moshi, United Republic of Tanzania.; Institute of Public Health, Community Health Department, Kilimanjaro Christian Medical University College, P.O.Box2240, Moshi, Tanzania., Temu EM; Internal Medicine Department, Kilimanjaro Christian Medical Center, P.O.Box3010, Moshi, United Republic of Tanzania., Nkwama ML; Internal Medicine Department, Kilimanjaro Christian Medical Center, P.O.Box3010, Moshi, United Republic of Tanzania., Pyuza JJ; Internal Medicine Department, Kilimanjaro Christian Medical Center, P.O.Box3010, Moshi, United Republic of Tanzania.; Institute of Public Health, Community Health Department, Kilimanjaro Christian Medical University College, P.O.Box2240, Moshi, Tanzania., Kilonzo KG; Internal Medicine Department, Kilimanjaro Christian Medical Center, P.O.Box3010, Moshi, United Republic of Tanzania.; Institute of Public Health, Community Health Department, Kilimanjaro Christian Medical University College, P.O.Box2240, Moshi, Tanzania., Lyamuya FS; Internal Medicine Department, Kilimanjaro Christian Medical Center, P.O.Box3010, Moshi, United Republic of Tanzania.; Institute of Public Health, Community Health Department, Kilimanjaro Christian Medical University College, P.O.Box2240, Moshi, Tanzania., Maro VP; Institute of Public Health, Community Health Department, Kilimanjaro Christian Medical University College, P.O.Box2240, Moshi, Tanzania.
المصدر: BMC infectious diseases [BMC Infect Dis] 2018 Sep 21; Vol. 18 (1), pp. 474. Date of Electronic Publication: 2018 Sep 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Health Personnel/*statistics & numerical data , Hepatitis B/*diagnosis, Adult ; Blood Transfusion ; Cross-Sectional Studies ; Female ; Hepatitis B/epidemiology ; Hepatitis B Surface Antigens/blood ; Humans ; Male ; Middle Aged ; Odds Ratio ; Prevalence ; Surveys and Questionnaires ; Tanzania/epidemiology ; Tertiary Care Centers ; Young Adult
مستخلص: Background: Hepatitis B virus infection is a global health problem with the highest prevalence in East Asia and Sub-Saharan Africa. The majority of infected people, including healthcare workers are unaware of their status. This study is aimed to determining seroprevalence of hepatitis B virus infection and associated factors among healthcare workers in northern Tanzania.
Methods: This cross-sectional study included 442 healthcare workers (HCWs) from a tertiary and teaching hospital in Tanzania before the nationwide hepatitis B vaccination campaign in 2004. Questionnaire- based interviews were used to obtain detailed histories of the following: demographic characteristics; occupation risks such splash and needle stick injuries or other invasive procedure such as intravenous, intramuscular or subcutaneous injections; history of blood transfusion and surgeries, as well as HCWs'knowledge of HBV. Serological markers of HBV were done using Laborex HBsAg rapid test. Serology was done at zero months and repeated after six months ( bioscienceinternational.co.ke/rapid-test-laborex.html HBsAg Piazzale-milano-2, Italy [Accessed on November 2017]). Chi-square (χ 2 ) tests were used to compare proportion of HBV infection by different HCWs characteristics. Multivariable logistic regression was used to determine factors associated with HBV infection.
Results: A total of 450 surveys were sent out, with a 98.2% response rate. Among the 442 HCWs who answered the questionnaire, the prevalence of chronic hepatitis B virus infection was 5.7% (25/442). Only 50 (11.3%) of HCWs were aware of the HBV status. During the second HBsAg testing which was done after six months one participant sero-converted hence was excluded. Adjusted for other factors, history of blood transfusion significantly increased the odds of HBV infection (OR = 21.44, 95%CI 6.05, 76.01, p < 0.001) while HBV vaccine uptake was protective against HBV infection (OR = 0.06, 95%CI 0.02, 0.26, p < 0.001). The majority of HCWs with chronic HBV infection had poor to fare knowledge about HBV infection but this was not statistically significant when controlled for confounding.
Conclusions: Prevalence of HBV among health care workers was 5.7% which is similar to national prevalence. Although the response rate to take part in the study was good but knowledge on HBV infection among HCWs was unsatisfactory. History of blood transfusion increased risks while vaccine uptake decreased the risk of HBV infection. This study recommends continues vaccinating HCWs together with continues medical education all over the country. We also recommend documentation of vaccination evidence should be asked before employment of HCWs in order to sensitize more uptakes of vaccinations. Although we didn't assess the use of personal protective equipment but we encourage HCWs to abide strictly on universal protections against nosocomial infections.
References: BMC Infect Dis. 2015 Sep 23;15:386. (PMID: 26399765)
J Med Virol. 2010 Sep;82(9):1569-75. (PMID: 20648611)
Med Lav. 2005 Jan-Feb;96(1):80-6. (PMID: 15847111)
Korean J Fam Med. 2017 Jan;38(1):21-27. (PMID: 28197329)
Afr Health Sci. 2009 Jun;9(2):98-108. (PMID: 19652743)
Vaccine. 2006 Nov 17;24(47-48):6930-7. (PMID: 17027122)
BMC Infect Dis. 2010 Jun 29;10:191. (PMID: 20587047)
Vaccine. 2014 Aug 27;32(38):4876-80. (PMID: 24161573)
Healthcare (Basel). 2017 Mar 07;5(1):. (PMID: 28272332)
BMC Pregnancy Childbirth. 2017 Apr 7;17(1):109. (PMID: 28388879)
J Trop Med. 2018 Jan 30;2018:4239646. (PMID: 29666656)
Tanzan J Health Res. 2014 Jan;16(1):9-15. (PMID: 26867267)
BMC Infect Dis. 2010 Jul 15;10:208. (PMID: 20630111)
J Virol. 2013 Nov;87(22):12196-206. (PMID: 24006443)
BMC Infect Dis. 2015 Jan 31;15:30. (PMID: 25637342)
BMC Res Notes. 2016 Feb 15;9:94. (PMID: 26879949)
Am J Trop Med Hyg. 2016 May 4;94(5):1100-2. (PMID: 26928835)
MMWR Recomm Rep. 2013 Dec 20;62(RR-10):1-19. (PMID: 24352112)
BMC Public Health. 2006 Jan 30;6:21. (PMID: 16445860)
BMC Public Health. 2016 Aug 03;15:706. (PMID: 27487845)
Niger J Clin Pract. 2015 Mar-Apr;18(2):276-81. (PMID: 25666007)
J Epidemiol Glob Health. 2016 Dec;6(4):229-241. (PMID: 27154428)
فهرسة مساهمة: Keywords: Healthcare workers; Hepatitis B virus; Risk factors; Tanzania
المشرفين على المادة: 0 (Hepatitis B Surface Antigens)
تواريخ الأحداث: Date Created: 20180923 Date Completed: 20181031 Latest Revision: 20181114
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6151054
DOI: 10.1186/s12879-018-3376-2
PMID: 30241503
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2334
DOI:10.1186/s12879-018-3376-2