دورية أكاديمية
Seeking universal detectors for analytical characterizations.
| العنوان: | Seeking universal detectors for analytical characterizations. |
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| المؤلفون: | Zhang K; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States. Electronic address: zhang.kelly@gene.com., Kurita KL; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Venkatramani C; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Russell D; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States. |
| المصدر: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2019 Jan 05; Vol. 162, pp. 192-204. Date of Electronic Publication: 2018 Sep 19. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2006->: London : Elsevier Science Original Publication: Oxford ; New York : Pergamon Press, c1983- |
| مواضيع طبية MeSH: | Chemistry, Pharmaceutical/*instrumentation , Pharmaceutical Preparations/*analysis , Technology, Pharmaceutical/*instrumentation, Equipment Design ; Reproducibility of Results |
| مستخلص: | It is highly desirable to have a universal detector that can detect all types of compounds and give a uniform response regardless of the physiochemical properties of the compounds. With such a universal detector, all components in a sample can be accurately quantified without the need for individual standards. This is especially needed for the characterization of unknowns and for non-targeted analysis, or for samples that have no isolated standards available for each component. Over the years, much effort has been put into seeking a universal detection technology. In this review, we discuss the commonly used detectors for analytical characterization, including UV, RI, ELSD, CAD, CLND, FID, VUV, MS, NMR, and hyphenated detection, with the focuses on the "universal" features of these detectors regarding the types of molecules they can detect and the uniformity of responses. (Copyright © 2018 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Characterization; Qualification; Quantification; Response factor; Universal detectors |
| المشرفين على المادة: | 0 (Pharmaceutical Preparations) |
| تواريخ الأحداث: | Date Created: 20180929 Date Completed: 20190122 Latest Revision: 20190122 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.jpba.2018.09.029 |
| PMID: | 30265979 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-264X |
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| DOI: | 10.1016/j.jpba.2018.09.029 |