دورية أكاديمية
High five-year mortality rates of ischemic stroke subtypes: A prospective cohort study in Brazil.
| العنوان: | High five-year mortality rates of ischemic stroke subtypes: A prospective cohort study in Brazil. |
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| المؤلفون: | Cabral NL; 1 Joinville Stroke Registry, Joinville, Brazil.; 2 University of Joinville Region, Joinville, Brazil., Nagel V; 1 Joinville Stroke Registry, Joinville, Brazil., Conforto AB; 3 Neurology Clinical Division, Hospital das Clínicas/Sao Paulo University, Hospital Israelita Albert Einstein, São Paulo, Brazil., Magalhaes PS; 2 University of Joinville Region, Joinville, Brazil., Venancio VG; 2 University of Joinville Region, Joinville, Brazil., Safanelli J; 2 University of Joinville Region, Joinville, Brazil., Ibiapina F; 4 Hospital Municipal São José, Joinville, Brazil., Mazin S; 5 Department of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., França P; 1 Joinville Stroke Registry, Joinville, Brazil., Liberato RM; 2 University of Joinville Region, Joinville, Brazil., Longo A; 4 Hospital Municipal São José, Joinville, Brazil., Zetola VF; 6 Neurology Department, Paraná Federal University, Curitiba, Brazil. |
| المصدر: | International journal of stroke : official journal of the International Stroke Society [Int J Stroke] 2019 Jul; Vol. 14 (5), pp. 491-499. Date of Electronic Publication: 2018 Oct 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 101274068 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4949 (Electronic) Linking ISSN: 17474930 NLM ISO Abbreviation: Int J Stroke Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : Thousand Oaks, CA : SAGE Publications Original Publication: Oxford, UK : Blackwell Pub., c2005- |
| مواضيع طبية MeSH: | Stroke/*diagnosis , Stroke/*mortality, Aged ; Brazil/epidemiology ; Disability Evaluation ; Female ; Humans ; Male ; Middle Aged ; Poverty/statistics & numerical data ; Prospective Studies ; Recurrence ; Survival Analysis ; Time Factors |
| مستخلص: | Background: Studies regarding long-term outcomes of ischemic stroke subtypes are scarce in low- and middle-income countries. We aimed to measure the five-year prognosis of ischemic stroke subtypes in Joinville, Brazil. Methods: All first-ever ischemic strokes that occurred in Joinville in 2010 were followed-up for five years. Results: We included 334 ischemic stroke patients. Over five years, 156 died, 51 had a recurrent stroke, and 128 were free of recurrent stroke. The overall cumulative risk of death was 17% (95% CI, 13% to 22%) at 30 days and 47% (95% CI, 41% to 52%) after five years. Undetermined with incomplete investigation ischemic stroke had a significantly worse survival probability (β -4.91; 95% CI, -6.31 to -3.50; p < 0.001), followed by cardioembolic ischemic stroke (β -3.07; 95% CI, -4.32 to -1.83; p < 0.001) and large artery disease ischemic stroke (β -1.95; 95% CI, -3.30 to -0.60; p = 0.005). The survival probability of undetermined with negative investigation or cryptogenic ischemic stroke did not differ significantly from small artery disease ischemic stroke (β -1.022; 95% CI, -3.37 to -1.43; p = 0.414). The five-year mortality for small artery disease ischemic stroke was 30% (95% CI, 22% to 39%) and 47% (95% CI, 35% to 60%) for large artery ischemic stroke. The risk of stroke recurrence was 2% in the first year and 5% in the second year. The proportion of disability among survivors in the first month ranged from 8% (95% CI, 3-15) for small artery disease ischemic stroke to 40% (95% CI, 30-52) for cardioembolic ischemic stroke patients. Conclusions: Cardioembolic and undetermined with incomplete investigation ischemic stroke sub-types have a poor long-term prognosis. An alarming finding was that our patients with both small and large artery ischemic stroke had higher five-year mortality rates compared with subjects from high-income countries. |
| فهرسة مساهمة: | Keywords: Ischemic stroke subtype; epidemiology; incidence; recurrence; stroke prognosis; survival |
| تواريخ الأحداث: | Date Created: 20181010 Date Completed: 20200210 Latest Revision: 20200210 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1177/1747493018806197 |
| PMID: | 30299229 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1747-4949 |
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| DOI: | 10.1177/1747493018806197 |