دورية أكاديمية
أعرض في EDS

Using principal component analysis to describe the midfacial deformities in patients with craniofacial microsomia.

التفاصيل البيبلوغرافية
العنوان: Using principal component analysis to describe the midfacial deformities in patients with craniofacial microsomia.
المؤلفون: Maas BDPJ; The Craniofacial Unit, Great Ormond Street Hospital, Great Ormond St, WC1N 3JH, London, United Kingdom; The Dutch Craniofacial Centre, Department of Oral and Maxillofacial Surgery, Erasmus University Medical Centre, 's Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. Electronic address: brittamaas91@gmail.com., Pluijmers BI; The Dutch Craniofacial Centre, Department of Oral and Maxillofacial Surgery, Erasmus University Medical Centre, 's Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands., Knoops PGM; The Craniofacial Unit, Great Ormond Street Hospital, Great Ormond St, WC1N 3JH, London, United Kingdom., Ruff C; Medical Physics Department, University College London, Gower St, WC1E 6BT, London, United Kingdom., Koudstaal MJ; The Craniofacial Unit, Great Ormond Street Hospital, Great Ormond St, WC1N 3JH, London, United Kingdom; The Dutch Craniofacial Centre, Department of Oral and Maxillofacial Surgery, Erasmus University Medical Centre, 's Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands., Dunaway D; The Craniofacial Unit, Great Ormond Street Hospital, Great Ormond St, WC1N 3JH, London, United Kingdom.
المصدر: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery [J Craniomaxillofac Surg] 2018 Dec; Vol. 46 (12), pp. 2032-2041. Date of Electronic Publication: 2018 Sep 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Scotland NLM ID: 8704309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4119 (Electronic) Linking ISSN: 10105182 NLM ISO Abbreviation: J Craniomaxillofac Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: Edinburgh : Elsevier
Original Publication: Stuttgart ; New York : Thieme, [c1986-
مواضيع طبية MeSH: Principal Component Analysis*, Face/*abnormalities , Goldenhar Syndrome/*pathology, Anatomic Landmarks ; Child ; Female ; Humans ; Male ; Phenotype
مستخلص: Purpose: Craniofacial microsomia (CFM) is the result of a disturbance in embryologic development and is characterised by an asymmetric, mostly unilateral facial underdevelopment. The aim of this study is to understand the midfacial involvement in CFM using principal component analysis (PCA).
Materials and Methods: Pre-operative data from 19 CFM and 23 control patients were collected. A set of 71 landmarks was placed on three-dimensional (3D) reconstructions of all skulls to compare both populations. PCA visualised variation within both groups and calculated the vector of change. Linear measurements were taken to compare ratios between the populations and between the affected and unaffected sides in CFM patients.
Results: PCA defined a vector that described shape changes between both populations. Videos showed the variation within the control and CFM group and the transformation from a mean CFM skull into a normal phenotype. Linear measurements showed a significant difference between the affected and unaffected sides in CFM patients.
Conclusion: PCA has not been applied on asymmetrical data before, but it has proved to be a useful method to describe CFM. The virtual normalisation of a mean CFM skull enables visualisation of the bony shape changes, which is promising to delineate and to plan surgical correction and could be used as an outcome measure.
(Crown Copyright © 2018. Published by Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: Craniofacial abnormalities; Hemifacial microsomia; Midface; Principal component analysis; Skull
تواريخ الأحداث: Date Created: 20181016 Date Completed: 20190503 Latest Revision: 20190503
رمز التحديث: 20231215
DOI: 10.1016/j.jcms.2018.09.019
PMID: 30318324
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-4119
DOI:10.1016/j.jcms.2018.09.019