دورية أكاديمية
Antimicrobial photodynamic activity of rose bengal conjugated multi walled carbon nanotubes against planktonic cells and biofilm of Escherichia coli.
| العنوان: | Antimicrobial photodynamic activity of rose bengal conjugated multi walled carbon nanotubes against planktonic cells and biofilm of Escherichia coli. |
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| المؤلفون: | Vt A; Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, 605 014, India., Paramanantham P; Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, 605 014, India., Sb SL; Department of Physics, School of Physical, Chemical & Applied Sciences, Pondicherry University, Puducherry, 605014, India., Sharan A; Department of Physics, School of Physical, Chemical & Applied Sciences, Pondicherry University, Puducherry, 605014, India., Alsaedi MH; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia., Dawoud TMS; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia., Asad S; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia., Busi S; Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, 605 014, India. Electronic address: siddhardha.busi@gmail.com. |
| المصدر: | Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2018 Dec; Vol. 24, pp. 300-310. Date of Electronic Publication: 2018 Oct 17. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101226123 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1597 (Electronic) Linking ISSN: 15721000 NLM ISO Abbreviation: Photodiagnosis Photodyn Ther Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam ; Boston : Elsevier, c2004- |
| مواضيع طبية MeSH: | Biofilms/*drug effects , Escherichia coli/*drug effects , Photochemotherapy/*methods , Photosensitizing Agents/*pharmacology , Plankton/*drug effects , Rose Bengal/*pharmacology, Lasers, Semiconductor ; Nanotubes, Carbon/chemistry ; Photosensitizing Agents/administration & dosage ; Plankton/microbiology ; Reactive Oxygen Species/metabolism ; Rose Bengal/administration & dosage |
| مستخلص: | Background: The global threat of antimicrobial resistance especially due to the bacterial biofilms has engaged researchers in the search of new treatment modalities. Antimicrobial photodynamic inactivation (aPDI) is one of the alternative treatment modalities which kills bacteria by generating endogenous reactive oxygen species (ROS). In this work authors evaluated the antibacterial and antibiofilm efficacy of rose Bengal (RB) conjugated to CNT against E. coli. Methods: The interaction of anionic dye to the CNT was studied using UV-vis spectroscopy, HRTEM, FTIR and spectrofluorometry. Phototoxicity of RBCNT conjugate against E. coli was studied using a green light of 50 mW and radiant exposure of 1674.7 J/ cm 2 for 10 min. The antibiofilm activity and mechanism of action of RBCNT conjugate in presence of light was evaluated. Results: The loading and encapsulation was found to be 15.46 ± 1.05 and 61.85 ± 4.23% respectively. The photodynamic inactivation of planktonic cells of E. coli was found to 5.46 and 3.56 log Conclusion: This report has concluded the efficient photodynamic inactivation occurred in Gram negative bacteria E. coli due to the increased production of ROS inside the bacterial cells. Hence, the newly synthesized RBCNT conjugate can be efficiently utilized to control infections caused by E. coli. (Copyright © 2018 Elsevier B.V. All rights reserved.) |
| التعليقات: | Erratum in: Photodiagnosis Photodyn Ther. 2021 Sep;35:102363. (PMID: 34517574) |
| فهرسة مساهمة: | Keywords: Antimicrobial photodynamic inactivation; Carbon nanotubes; Escherichia coli; RBCNT; Reactive oxygen species; Rose Bengal |
| المشرفين على المادة: | 0 (Nanotubes, Carbon) 0 (Photosensitizing Agents) 0 (Reactive Oxygen Species) 1ZPG1ELY14 (Rose Bengal) |
| تواريخ الأحداث: | Date Created: 20181021 Date Completed: 20190517 Latest Revision: 20210914 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.pdpdt.2018.10.013 |
| PMID: | 30342101 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1873-1597 |
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| DOI: | 10.1016/j.pdpdt.2018.10.013 |