دورية أكاديمية
أعرض في EDS

Effect of high flow transnasal dry air on core body temperature in intubated human subjects.

التفاصيل البيبلوغرافية
العنوان: Effect of high flow transnasal dry air on core body temperature in intubated human subjects.
المؤلفون: Chava R; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zviman M; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Assis FR; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Raghavan MS; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Halperin H; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Maqbool F; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Geocadin R; Department of Neuroanesthesia and Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Quinones-Hinojosa A; Department of Neuroanesthesia and Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kolandaivelu A; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Rosen BA; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Tandri H; Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: htandri1@jhmi.edu.
المصدر: Resuscitation [Resuscitation] 2019 Jan; Vol. 134, pp. 49-54. Date of Electronic Publication: 2018 Oct 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier/north-Holland Biomedical Press Country of Publication: Ireland NLM ID: 0332173 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1570 (Electronic) Linking ISSN: 03009572 NLM ISO Abbreviation: Resuscitation Subsets: MEDLINE
أسماء مطبوعة: Publication: Limerick : Elsevier/north-Holland Biomedical Press
Original Publication: London, Middlesex Pub. Co.
مواضيع طبية MeSH: Body Temperature Regulation*, Hypothermia, Induced/*methods, Adult ; Case-Control Studies ; Esophagus/physiology ; Female ; Humans ; Male ; Middle Aged ; Nasal Mucosa/physiology ; Respiration, Artificial/methods
مستخلص: Purpose: Early initiation of hypothermia is recommended in the setting of cardiac arrest. Current hypothermia methods are invasive and expensive and not applicable in ambulatory settings. We investigated the evaporative cooling effect of high flow transnasal dry air on core esophageal temperature in human volunteers.
Methods & Results: A total of 32 subjects (mean age 53.2 ± 9.3 yrs., mean weight 90 ± 17 kg) presenting for elective electrophysiological procedures were enrolled for the study. Half of the subjects were men. Following general anesthesia induction, high flow (30 LPM) medical grade ambient dry air with a relative humidity ∼20% was administered through a nasal mask for 60 min. Core temperature was monitored at the distal esophagus. Half of the subjects (16/32) were subject to high flow air and the remainder served as controls. Over a 1-h period, mean esophageal temperature decreased from 36.1 ± 0.3 °C to 35.5 ± 0.1 °C in the test subjects (p < 0.05). No significant change in temperature was observed in the control subjects (36.3 ± 0.3 °C to 36.2 ± 0.2 °C, p = NS). No adverse events occurred.
Conclusion: Transnasal high flow dry air through the nasopharynx reduces core body temperature. This mechanism can be harnessed to induce hypothermia in patients where clinically indicated without any deleteriouseffects in a short time exposure.
(Copyright © 2018 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Core body temperature; Evaporative cooling; Neurogenic fever; Therapeutic hypothermia; Transnasal high flow air
تواريخ الأحداث: Date Created: 20181026 Date Completed: 20200309 Latest Revision: 20200309
رمز التحديث: 20231215
DOI: 10.1016/j.resuscitation.2018.10.020
PMID: 30359664
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-1570
DOI:10.1016/j.resuscitation.2018.10.020