دورية أكاديمية
Pineal Cyst-Related Aqueductal Stenosis as Cause of Intractable Headaches in Nonhydrocephalic Patients.
| العنوان: | Pineal Cyst-Related Aqueductal Stenosis as Cause of Intractable Headaches in Nonhydrocephalic Patients. |
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| المؤلفون: | Pitskhelauri DI; Department of Neurooncology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia., Konovalov AN; Department of Neurooncology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia., Abramov IT; Department of Neurooncology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia. Electronic address: irakliyabramov@gmail.com., Danilov GV; Department of Neurooncology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia., Pronin IN; Department of Neuroradiology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia., Alexandrova EV; Department of Neurology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia., Serova NK; Department of Neuroopththalmology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia., Sanikidze AZ; Department of Neurooncology, Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia. |
| المصدر: | World neurosurgery [World Neurosurg] 2019 Mar; Vol. 123, pp. e147-e155. Date of Electronic Publication: 2018 Nov 22. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 101528275 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-8769 (Electronic) Linking ISSN: 18788750 NLM ISO Abbreviation: World Neurosurg Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York : Elsevier |
| مواضيع طبية MeSH: | Central Nervous System Cysts/*complications , Headache/*etiology , Hydrocephalus/*etiology , Pinealoma/*complications, Adolescent ; Adult ; Central Nervous System Cysts/diagnostic imaging ; Central Nervous System Cysts/physiopathology ; Central Nervous System Cysts/surgery ; Child ; Child, Preschool ; Female ; Headache/diagnostic imaging ; Headache/physiopathology ; Headache/surgery ; Humans ; Hydrocephalus/diagnostic imaging ; Hydrocephalus/physiopathology ; Hydrocephalus/surgery ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neurosurgical Procedures ; Pinealoma/diagnostic imaging ; Pinealoma/physiopathology ; Pinealoma/surgery ; Retrospective Studies ; Treatment Outcome ; Young Adult |
| مستخلص: | Background: Pineal cysts (PCs) are histologically benign lesions of the pineal gland. Although the majority of PCs are asymptomatic, some cases are ambiguous and accompanied by nonspecific symptoms of variable severity. We suggested that disabling headache in nonhydrocephalic patients with PCs is associated with cerebral aqueduct (CAq) stenosis. Methods: A retrospective analysis was conducted in patients with PCs suffering from headache without secondary hydrocephalus who underwent surgical resection at Burdenko Neurosurgery Center between 1995 and 2016. All available medical records and radiographic images were retrospectively assessed in these patients. The comparison groups included 22 patients with nonoperated PCs and 25 healthy individuals. Specific magnetic resonance imaging measures were selected to assess the morphometry of the CAq and degree of the stenosis. Results: In 25 patients (82%) we observed clinical improvement after surgery in a follow-up period. Among those with improvement, 10 of them (40%) experienced total relief and 15 of them (60%) had marked headache diminishment. In 5 patients the headache remained persistent. The preoperative rostral CAq diameter appeared to be significantly narrower (P = 0.0011045), and the preoperative rostral/caudal diameter ratio (Rd/Cd) was found to be lower (P = 0.004391) in patients who recovered from headache versus those who did not. Conclusion: The results indicate a statistically significant relationship between the changes in the CAq morphometrics and the clinical outcome in postoperative period. Surgical removal of symptomatic pineal cysts in patients without hydrocephalus can be considered as an effective treatment. However, a thorough preoperative examination and patient selection should be conducted in every case. (Copyright © 2018 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Cerebral aqueduct; Headache; Magnetic resonance imaging; Neurosurgery; Pineal cyst |
| تواريخ الأحداث: | Date Created: 20181124 Date Completed: 20190403 Latest Revision: 20190403 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.wneu.2018.11.096 |
| PMID: | 30468924 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1878-8769 |
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| DOI: | 10.1016/j.wneu.2018.11.096 |