Prevalence of Human Papillomavirus, Human Immunodeficiency Virus, and Other Sexually Transmitted Infections Among Men Who Have Sex With Men in Togo: A National Cross-sectional Survey.

التفاصيل البيبلوغرافية
العنوان:	Prevalence of Human Papillomavirus, Human Immunodeficiency Virus, and Other Sexually Transmitted Infections Among Men Who Have Sex With Men in Togo: A National Cross-sectional Survey.
المؤلفون:	Ferré VM; Institut national de la santé et de la recherche médicale (INSERM), Infection, Antimicrobials, Modelling, Evolution, Unité Mixte de Recherche.; Université Paris Diderot, Sorbonne Paris Cité, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Laboratoire de Virologie, Paris, France., Gbeasor-Komlanvi FA; Université de Lomé, Faculté des Sciences de la Santé, Département de Santé Publique.; Centre Africain de Recherche en Epidémiologie et en Santé Publique., Collin G; Institut national de la santé et de la recherche médicale (INSERM), Infection, Antimicrobials, Modelling, Evolution, Unité Mixte de Recherche.; Université Paris Diderot, Sorbonne Paris Cité, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Laboratoire de Virologie, Paris, France., Dagnra AC; Université de Lomé, Centre de Biologie Moléculaire et d'Immunologie.; Programme national de lutte contre le sida et les infections sexuellement transmissibles, Togo., Le Hingrat Q; Institut national de la santé et de la recherche médicale (INSERM), Infection, Antimicrobials, Modelling, Evolution, Unité Mixte de Recherche.; Université Paris Diderot, Sorbonne Paris Cité, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Laboratoire de Virologie, Paris, France., Jaquet A; Institut de santé publique, d'épidémiologie et de développement, Université de Bordeaux and Centre INSERM U1219, Bordeaux Population Health, France., Salou M; Université de Lomé, Centre de Biologie Moléculaire et d'Immunologie., Descamps D; Institut national de la santé et de la recherche médicale (INSERM), Infection, Antimicrobials, Modelling, Evolution, Unité Mixte de Recherche.; Université Paris Diderot, Sorbonne Paris Cité, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Laboratoire de Virologie, Paris, France., Charpentier C; Institut national de la santé et de la recherche médicale (INSERM), Infection, Antimicrobials, Modelling, Evolution, Unité Mixte de Recherche.; Université Paris Diderot, Sorbonne Paris Cité, Paris, France.; Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Laboratoire de Virologie, Paris, France., Ekouevi DK; Université de Lomé, Faculté des Sciences de la Santé, Département de Santé Publique.; Centre Africain de Recherche en Epidémiologie et en Santé Publique.; Institut de santé publique, d'épidémiologie et de développement, Université de Bordeaux and Centre INSERM U1219, Bordeaux Population Health, France.
المصدر:	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2019 Aug 30; Vol. 69 (6), pp. 1019-1026.
نوع المنشور:	Journal Article; Research Support, Non-U.S. Gov't
اللغة:	English
بيانات الدورية:	Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
أسماء مطبوعة:	Publication: Jan. 2011- : Oxford : Oxford University Press Original Publication: Chicago, IL : The University of Chicago Press, c1992-
مواضيع طبية MeSH:	Homosexuality, Male, HIV Infections/epidemiology , Papillomavirus Infections/epidemiology , Sexually Transmitted Diseases/epidemiology, Adolescent ; Adult ; Coinfection ; Cross-Sectional Studies ; Disease Susceptibility ; Female ; HIV ; HIV Infections/transmission ; HIV Infections/virology ; Humans ; Male ; Papillomaviridae/classification ; Papillomaviridae/genetics ; Papillomavirus Infections/transmission ; Papillomavirus Infections/virology ; Prevalence ; Public Health Surveillance ; Risk Factors ; Sexually Transmitted Diseases/etiology ; Sexually Transmitted Diseases/transmission ; Surveys and Questionnaires ; Togo/epidemiology ; Young Adult
مستخلص:	Background: Sub-Saharan Africa is a region of both high human immunodeficiency virus (HIV) and anal cancer incidence. We conducted the first national study in Togo to assess human papillomavirus (HPV), HIV, and other sexually transmitted infection (STI) prevalence among men who have sex with men (MSM). Methods: A multicentric cross-sectional study was conducted among MSM recruited in 4 Togolese cities. Anal swabs were collected to test HPV, herpes simplex virus (HSV), and 7 STIs. Results: Among the 207 MSM, HIV and high-risk HPV (hrHPV) overall prevalence were 26.1% and 44.9%, respectively. The most common hrHPV types were HPV-35 (15.0%) and HPV-16 (13.0%). Prevalence of hrHPV and multiple HPV infections were higher among HIV-infected than among HIV-uninfected MSM (85.2% vs 30.7%, P < 10-5 and 85.2% vs 28.7%, P < 10-5, respectively). Other STIs, except hepatitis B virus, were also more prevalent among HIV-infected MSM (Neisseria gonorrhoeae, P = .03; Mycoplasma genitalium, P = .04; HSV-2, P = .001; and a trend for Chlamydia trachomatis, P = .06). In multivariate analysis (adjusted odds ratio [95% confidence interval]), HIV (10.1 [4.0-25.6]), living in Lomé (2.8 [1.1-7.1]), HSV-2 excretion (26.7 [2.9-244.3]), C. trachomatis (11.7 [2.3-58.9]), and M. genitalium infection (9.6 [3.1-29.9]) were associated with increased risk of hrHPV infection. Conclusions: We report a high burden of anal STIs with an unusual hrHPV type distribution among MSM, highlighting the critical need of implementation of a national strategy regarding prevention of STIs and vaccination against HPV. (© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.)
فهرسة مساهمة:	Keywords: HIV; HPV; MSM; STIs; Togo
تواريخ الأحداث:	Date Created: 20181207 Date Completed: 20200901 Latest Revision: 20220409
رمز التحديث:	20240628
DOI:	10.1093/cid/ciy1012
PMID:	30520971
قاعدة البيانات:	MEDLINE

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تدمد:	1537-6591
DOI:	10.1093/cid/ciy1012