دورية أكاديمية
Differences at surgery between patients with bicuspid and tricuspid aortic valves.
| العنوان: | Differences at surgery between patients with bicuspid and tricuspid aortic valves. |
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| المؤلفون: | Cozijnsen L; Department of Cardiology, Gelre Hospital, Apeldoorn, The Netherlands. l.cozijnsen@gelre.nl., van der Zaag-Loonen HJ; Department of Epidemiology, Gelre Hospital, Apeldoorn, The Netherlands., Cozijnsen MA; Department of Paediatric Gastroenterology and Hepatology, Erasmus Medical Centre, Rotterdam, The Netherlands., Braam RL; Department of Cardiology, Gelre Hospital, Apeldoorn, The Netherlands., Heijmen RH; Department of Cardiothoracic Surgery, Nieuwegein, The Netherlands., Bouma BJ; Department of Cardiology, Amsterdam University Medical Centre, location AMC, Amsterdam, The Netherlands., Mulder BJM; Department of Cardiology, Amsterdam University Medical Centre, location AMC, Amsterdam, The Netherlands. |
| المصدر: | Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation [Neth Heart J] 2019 Feb; Vol. 27 (2), pp. 93-99. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bohn Stafleu van Loghum Country of Publication: Netherlands NLM ID: 101095458 Publication Model: Print Cited Medium: Print ISSN: 1568-5888 (Print) Linking ISSN: 15685888 NLM ISO Abbreviation: Neth Heart J Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: Houten : Bohn Stafleu van Loghum Original Publication: Leusden, The Netherlands : Mediselect bv, c2001- |
| مستخلص: | Aim: To determine differences in surgical procedures and clinical characteristics at the time of surgery between native bicuspid aortic valves (BAV) and tricuspid aortic valves (TAV) in patients being followed up after aortic valve surgery (AVS). Methods: In this retrospective cohort study in a non-academic hospital, we identified patients who had a surgeon's report of the number of native valve cusps and were still being followed up. We selected patients with BAV and TAV, and used multivariable regression analyses to identify associations between BAV-TAV and pre-specified clinical characteristics. Results: Of 439 patients, 140 had BAV (32%) and 299 TAV (68%). BAV patients were younger at the time of surgery (mean age 58.6 ± 13 years) than TAV patients (69.1 ± 12 years, p < 0.001) and were more often male (64% vs 53%; p = 0.029). Cardiovascular risk factors were less prevalent in BAV than in TAV patients at the time of surgery (hypertension (31% vs 55%), hypercholesterolaemia (29% vs 58%) and diabetes (7% vs 16%); all p < 0.005). Concomitant coronary artery bypass grafting (CABG) was performed less often in BAV than in TAV patients (14% vs 39%, p < 0.001), even when adjusted for confounders (adjusted odds ratio (adj.OR) 0.45; 95% CI: 0.25-0.83). In contrast, surgery of the proximal aorta was performed more often (31% vs 11%, respectively, p < 0.001; adj.OR 2.3; 95% CI: 1.3-4.0). Conclusions: Whereas mechanical stress is the supposed major driver of valvulopathy towards AVS in BAV, prevalent cardiovascular risk factors are a suspected driver towards the requirement for AVS and concomitant CABG in TAV, an observation based on surgical determination of the number of valve cusps. |
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| فهرسة مساهمة: | Keywords: Aortic stenosis; Aortic valve surgery; Bicuspid aortic valve; Cardiovascular risk factors; Native valve anatomy; Tricuspid aortic valve |
| تواريخ الأحداث: | Date Created: 20181215 Latest Revision: 20200929 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC6352617 |
| DOI: | 10.1007/s12471-018-1214-1 |
| PMID: | 30547414 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1568-5888 |
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| DOI: | 10.1007/s12471-018-1214-1 |