دورية أكاديمية
Phytochemical Analysis and Central Effects of Annona Muricata Linnaeus: Possible Involvement of the Gabaergic and Monoaminergic Systems.
| العنوان: | Phytochemical Analysis and Central Effects of Annona Muricata Linnaeus: Possible Involvement of the Gabaergic and Monoaminergic Systems. |
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| المؤلفون: | Souza DO; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Dos Santos Sales V; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., de Souza Rodrigues CK; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., de Oliveira LR; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Santiago Lemos IC; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., de Araújo Delmondes G; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Monteiro ÁB; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., do Nascimento EP; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Sobreira Dantas Nóbrega de Figuêiredo FR; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Martins da Costa JG; Laboratory of Research in Natural Products, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Pinto da Cruz GM; Laboratory of Pharmacology and Biophysiology, Faculty of Medicine Estácio of Juazeiro do Norte, 515 Tenente Raimundo Rocha, Juazeiro do Norte (CE), Brazil., de Barros Viana GS; Laboratory of Pharmacology and Biophysiology, Faculty of Medicine Estácio of Juazeiro do Norte, 515 Tenente Raimundo Rocha, Juazeiro do Norte (CE), Brazil., Barbosa R; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Alencar de Menezes IR; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil., Bezerra Felipe CF; Laboratory of Pharmacology and Experimental Biochemistry, Federal University of Paraíba, Cidade Universitária Pessoa (PB), Brazil., Kerntopf MR; Laboratory of Molecular Chemistry and Pharmacology, Regional University of Cariri Antonio Luis, Crato (CE), Brazil. |
| المصدر: | Iranian journal of pharmaceutical research : IJPR [Iran J Pharm Res] 2018 Fall; Vol. 17 (4), pp. 1306-1317. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Brieflands Country of Publication: Netherlands NLM ID: 101208407 Publication Model: Print Cited Medium: Print ISSN: 1735-0328 (Print) Linking ISSN: 17266882 NLM ISO Abbreviation: Iran J Pharm Res Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2022- : ['s-Hertogenbosch, The Netherlands] : Brieflands Original Publication: Tehran : School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services |
| مستخلص: | Annona muricata Linnaeus (Annonaceae), popularly known as graviola , is used in folk medicine as both sedative and anticonvulsant. This study correlates the neurochemical profile with the behavioral effects of the hydroalcoholic extract from the leaves of Annona muricata (HLEAM) in mice, proposing to elucidate their mechanism of action on the central nervous system. Flavonoids and phenolic compounds were identified and quantified by High Performance Liquid Chromatography (HPLC) method. The acute toxicity (median lethal dose - LD |
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| فهرسة مساهمة: | Keywords: Annona muricata; Anticonvulsant; Anxiolytic; GABAergic system; Monoaminergic system; Phenolic compounds; Sedative |
| تواريخ الأحداث: | Date Created: 20181221 Latest Revision: 20231004 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC6269576 |
| PMID: | 30568689 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1735-0328 |
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