التفاصيل البيبلوغرافية
| العنوان: |
Iridium-Catalyzed Radiosynthesis of Branched Allylic [ 18 F]Fluorides. |
| المؤلفون: |
Mixdorf JC; Department of Chemistry , University of Iowa , Iowa City , Iowa 52242 , United States., Sorlin AM; Department of Chemistry , University of Iowa , Iowa City , Iowa 52242 , United States., Dick DW; University of Iowa Hospitals and Clinics , University of Iowa , Iowa City , Iowa 52242 , United States., Nguyen HM; Department of Chemistry , Wayne State University , Detroit , Michigan 48202 , United States. |
| المصدر: |
Organic letters [Org Lett] 2019 Jan 04; Vol. 21 (1), pp. 60-64. Date of Electronic Publication: 2018 Dec 21. |
| نوع المنشور: |
Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: |
Original Publication: Washington, DC : American Chemical Society, c1999- |
| مستخلص: |
The rapid and operationally simple radiosynthesis of branched allylic [ 18 F]fluorides bearing a variety of functional groups, via iridium-catalyzed nucleophilic substitution reaction utilizing allylic trichloroacetimidates and [ 18 F]KF·Kryptofix[2.2.2] complex in 5-15 min at room temperature, is reported. The versatility of the allyl functional group of the resulting radiofluorinated products offers the benefit of being subsequently available for further functionalization. |
| تواريخ الأحداث: |
Date Created: 20181222 Latest Revision: 20210421 |
| رمز التحديث: |
20221213 |
| DOI: |
10.1021/acs.orglett.8b03496 |
| PMID: |
30575403 |
| قاعدة البيانات: |
MEDLINE |
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