Cervicomedullary primitive neuroectodermal tumor of the spine: Case report.

التفاصيل البيبلوغرافية
العنوان: Cervicomedullary primitive neuroectodermal tumor of the spine: Case report.
المؤلفون: Nery B; Department of Neurosurgery, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Pereira LCT; Department of Neurosurgery, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Costa RAF; Department of Neurosurgery, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Queiroz RM; Department of Radiology, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Abud LG; Department of Radiology, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Quaggio E; Department of Neurosurgery, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Coronatto LH; Department of Neurosurgery, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Prado IST; Department of Radiology, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Miyake CH; Department of Radiology, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil., Filho FB; Department of Internal Medicine, Hospital São Francisco, Ribeirão Preto, São Paulo, Brazil.
المصدر: Surgical neurology international [Surg Neurol Int] 2018 Nov 28; Vol. 9, pp. 241. Date of Electronic Publication: 2018 Nov 28 (Print Publication: 2018).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Scientific Scholar LLC Country of Publication: United States NLM ID: 101535836 Publication Model: eCollection Cited Medium: Print ISSN: 2229-5097 (Print) Linking ISSN: 21527806 NLM ISO Abbreviation: Surg Neurol Int Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Pittsford, NY, USA : Scientific Scholar LLC
Original Publication: Mumbai : Medknow
مستخلص: Background: Intramedullary primitive neuroectodermal tumors (PNETs) are tumors found rarely in the cervical region, with only five such cases described in the literature. The available literature contains only one report regarding cervicomedullary junction PNET.
Case Description: The authors present a case report of a 45-year-old male patient who had undergone urgent hospitalization owing to progressive tetraparesis and subtle impairment of respiratory function. He underwent magnetic resonance imaging, which showed an extensive enhancing cervical intramedullary tumor extending from C5 to the bulbar region. Since he developed severe impairment of respiratory function, he required tracheostomy. He then underwent microsurgery 2 days after his admission, and a partial tumor resection was performed. The pathological diagnosis of PNET of the cervicomedullary junction (CMJ) was made. He had slight worsening of strength after surgery with subsequent deterioration over the next 3 weeks. The tumor displayed aggressive growth; thus, radiotherapy was indicated. Unfortunately, he developed severe febrile neutropenia and died after 2 weeks of radiotherapy. Given the rarity of the condition, we wish to review the epidemiology, pathophysiology, and treatment options of his population.
Conclusion: Intramedullary PNETs of the cervical spine and CMJ are exceedingly rare in adults; treatment of such patients remains a challenge, despite the modern neurosurgical armamentarium that is available.
Competing Interests: There are no conflicts of interest.
References: J Neurooncol. 2000 May;47(3):189-94. (PMID: 11016735)
J Neurooncol. 2003 Jan;61(2):113-20. (PMID: 12622449)
Surg Neurol. 1992 Apr;37(4):307-12. (PMID: 1317609)
Clin Neurol Neurosurg. 2005 Aug;107(5):408-11. (PMID: 16023536)
J Neurooncol. 2006 Mar;77(1):65-72. (PMID: 16292490)
Clin Neurosurg. 2005;52:76-84. (PMID: 16626057)
J Neurosurg Spine. 2006 Jun;4(6):497-502. (PMID: 16776362)
Pediatr Neurosurg. 2007;43(1):1-6. (PMID: 17190980)
Ann Surg. 1925 Jun;81(6):1057-73. (PMID: 17865272)
Arch Pathol Lab Med. 2008 Jun;132(6):993-1007. (PMID: 18517285)
Neurol India. 2009 Sep-Oct;57(5):661-8. (PMID: 19934573)
Neurosurg Focus. 2011 Jan;30(1):E1. (PMID: 21194274)
Curr Neurol Neurosci Rep. 2011 Jun;11(3):320-8. (PMID: 21327734)
Neurol Med Chir (Tokyo). 2011;51(8):596-9. (PMID: 21869585)
Surg Neurol Int. 2011;2:155. (PMID: 22140640)
J Clin Oncol. 2012 Jan 10;30(2):e15-8. (PMID: 22147740)
J Child Neurol. 2013 Feb;28(2):246-50. (PMID: 22532539)
Surg Neurol Int. 2012;3:55. (PMID: 22629492)
J Clin Neurosci. 2012 Nov;19(11):1541-4. (PMID: 22981874)
J Craniovertebr Junction Spine. 2016 Apr-Jun;7(2):111-4. (PMID: 27217659)
BMC Res Notes. 2016 Sep 09;9(1):438. (PMID: 27613377)
Medicine (Baltimore). 2017 Dec;96(49):e9001. (PMID: 29245277)
فهرسة مساهمة: Keywords: Cervicomedullary; intramedullary; neuroectodermal tumor; pathology; primitive; treatment
تواريخ الأحداث: Date Created: 20190101 Latest Revision: 20220408
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6287338
DOI: 10.4103/sni.sni_41_18
PMID: 30595962
قاعدة البيانات: MEDLINE
الوصف
تدمد:2229-5097
DOI:10.4103/sni.sni_41_18