دورية أكاديمية
Derivation and external validation of the SHIeLD score for predicting outcome in normotensive pulmonary embolism.
| العنوان: | Derivation and external validation of the SHIeLD score for predicting outcome in normotensive pulmonary embolism. |
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| المؤلفون: | Freitas P; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal. Electronic address: pnfreitas@chlo.min-saude.pt., Santos AR; Internal Medicine Department, Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Ferreira AM; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Oliveira A; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Gonçalves M; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Corte-Real A; Internal Medicine Department III, Hospital Prof. Doutor Fernando Fonseca, Lisbon, Portugal., Lameiras C; Internal Medicine Department III, Hospital Prof. Doutor Fernando Fonseca, Lisbon, Portugal., Maurício J; Internal Medicine Department III, Hospital Prof. Doutor Fernando Fonseca, Lisbon, Portugal., Ornelas É; Internal Medicine Department III, Hospital Prof. Doutor Fernando Fonseca, Lisbon, Portugal., Matos C; Internal Medicine Department III, Hospital Prof. Doutor Fernando Fonseca, Lisbon, Portugal., Faria D; Cardiology Department, Hospital Professor Doutor Fernando Fonseca, Lisbon, Portugal., Augusto J; Cardiology Department, Hospital Professor Doutor Fernando Fonseca, Lisbon, Portugal., Simões J; Cardiology Department, Hospital Professor Doutor Fernando Fonseca, Lisbon, Portugal., Ferreira I; Internal Medicine Department, Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Pedroso A; Internal Medicine Department, Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Santos AC; Radiology Department, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Gago M; Radiology Department, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Oliveira JD; Radiology Department, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Antunes RM; Radiology Department, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Correia D; Radiology Department, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Lynce A; Internal Medicine Department, Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Brito J; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Aguiar C; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Ferreira J; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Morais C; Cardiology Department, Hospital Professor Doutor Fernando Fonseca, Lisbon, Portugal., Campos L; Internal Medicine Department, Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Raposo L; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal., Mendes M; Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal. |
| المصدر: | International journal of cardiology [Int J Cardiol] 2019 Apr 15; Vol. 281, pp. 119-124. Date of Electronic Publication: 2018 Dec 28. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981- |
| مواضيع طبية MeSH: | Severity of Illness Index*, Pulmonary Embolism/*diagnosis , Pulmonary Embolism/*physiopathology, Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Prognosis ; Reproducibility of Results ; Retrospective Studies ; Treatment Outcome |
| مستخلص: | Background: Identifying patients with normotensive pulmonary embolism (PE) who may benefit from thrombolysis remains challenging. We sought to develop and validate a score to predict 30-days PE-related mortality and/or rescue thrombolysis. Methods: We retrospectively assessed 554 patients with normotensive PE. Independent predictors of the studied endpoint were identified from variables available at admission in the emergency department and were used to create a score. The model was validated in 308 patients from a separate hospital. Results: A total of 64 patients died or needed rescue thrombolysis (44 in the derivation cohort). Four independent prognostic factors were identified: Shock index ≥ 1.0 (OR 3.33; 95% CI 1.40-7.93; P = 0.006), HypoxaemIa by the PaO Conclusions: A risk score to predict 30-days PE-related mortality and/or rescue thrombolysis in patients with normotensive PE was developed and validated. This score may assist physicians in selecting patients for closer monitoring or aggressive treatment strategy. (Copyright © 2018 Elsevier B.V. All rights reserved.) |
| التعليقات: | Comment in: Int J Cardiol. 2019 Apr 15;281:125-126. (PMID: 30711268) |
| فهرسة مساهمة: | Keywords: Biomarkers; NT-proBNP; Pulmonary embolism; Risk assessment; Troponin |
| تواريخ الأحداث: | Date Created: 20190115 Date Completed: 20191224 Latest Revision: 20191224 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.ijcard.2018.12.062 |
| PMID: | 30638984 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1874-1754 |
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| DOI: | 10.1016/j.ijcard.2018.12.062 |