دورية أكاديمية
Correlates of childhood trauma in children and adolescents with bipolar disorder spectrum: A preliminary study.
| العنوان: | Correlates of childhood trauma in children and adolescents with bipolar disorder spectrum: A preliminary study. |
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| المؤلفون: | Cazala F; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA. Electronic address: fcazala@mrn.org., Bauer IE; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA., Meyer TD; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA., Spiker DE; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA., Kazimi IF; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA., Zeni CP; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA., Zunta-Soares GB; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA., Soares JC; Department of Psychiatry and Behavioral Science, University of Texas Health Science Center, 1941 East Rd, Houston 77054, TX, USA. |
| المصدر: | Journal of affective disorders [J Affect Disord] 2019 Mar 15; Vol. 247, pp. 114-119. Date of Electronic Publication: 2018 Dec 10. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press. |
| مواضيع طبية MeSH: | Bipolar Disorder/*psychology , Child Abuse/*psychology, Adolescent ; Aggression ; Child ; Fear ; Female ; Humans ; Male ; Physical Abuse/psychology ; Sex Factors ; Suicidal Ideation ; Suicide/psychology ; Surveys and Questionnaires |
| مستخلص: | Objective: Histories of childhood trauma (CT) are risk factors for affect dysregulation and poor clinical outcomes in women with bipolar disorder (BD). While much is known about the link between BD and CT in adult patients, there is limited data on this research topic in pediatric BD (PBD). The present study aims to investigate the impact of CT on irritability, aggressive and suicidal behaviors in PBD patients across gender types. Methods: From 2013 to 2015, 59 PBD patients Aged 6-17 (30 female) were administered the Childhood Trauma Questionnaire (CTQ) along with scales assessing irritability (Affective Reactivity Index), aggression (Modified Overt Aggression Scale) and suicidal thoughts and behaviors (Columbia-Suicide Severity Rating Scale). We examined the severity of these behaviors across types of CT and gender using univariate regression analyses. Findings were adjusted for age, number of traumas, and CTQ denial score. Results: In PBD patients, analyses showed that the effect of physical abuse depended on gender, whereby females were more likely than males to engage in suicidal thoughts and behaviors (p < 0.05). Male gender and CT were strong determinants of irritability (p < 0.05). Violence against property and people was found to be reduced in females, and increased in males with a history of emotional and sexual abuse, respectively (p < 0.05). Conclusion: These preliminary findings highlight the significant impact of CT in PBD and suggest that gender may predict the risk for dysfunctional behaviors in PBD patients with CT. Future large scale, longitudinal, investigations focusing on fear processing and extinction may provide a deeper understanding of these gender differences, and their role in the course of BD. (Copyright © 2018. Published by Elsevier B.V.) |
| فهرسة مساهمة: | Keywords: Bipolar disorder; Childhood trauma; Gender; Pediatric; Suicide; Violence |
| تواريخ الأحداث: | Date Created: 20190120 Date Completed: 20190508 Latest Revision: 20190508 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.jad.2018.12.007 |
| PMID: | 30660020 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1573-2517 |
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| DOI: | 10.1016/j.jad.2018.12.007 |