دورية أكاديمية
Comparison of Nebulized Ketamine with Nebulized Magnesium Sulfate on the Incidence of Postoperative Sore Throat.
| العنوان: | Comparison of Nebulized Ketamine with Nebulized Magnesium Sulfate on the Incidence of Postoperative Sore Throat. |
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| المؤلفون: | Segaran S; Department of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India., Bacthavasalame AT; Department of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India., Venkatesh RR; Department of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India., Zachariah M; Department of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India., George SK; Department of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India., Kandasamy R; Department of Anaesthesiology and Critical Care, Pondicherry Institute of Medical Sciences, Puducherry, India. |
| المصدر: | Anesthesia, essays and researches [Anesth Essays Res] 2018 Oct-Dec; Vol. 12 (4), pp. 885-890. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications Country of Publication: India NLM ID: 101578762 Publication Model: Print Cited Medium: Print ISSN: 0259-1162 (Print) Linking ISSN: 22297685 NLM ISO Abbreviation: Anesth Essays Res Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Mumbai] : Medknow Publications |
| مستخلص: | Background: Postoperative sore throat (POST) is a known complication following general anesthesia requiring endotracheal intubation. Its incidence ranges from 21% to 65% and remains the eighth most undesirable postoperative event. Various measures have been tried to decrease the incidence of sore throat with various success rates. Aim: This study aimed at reducing the incidence of POST with ketamine and magnesium sulfate nebulization. Settings and Design: This study is a prospective randomized, double-blinded study. Materials and Methods: After Institutional Ethics Committee approval and written informed consent, 80 patients who fulfilled the inclusion and exclusion criteria were randomly divided into two groups to receive magnesium sulfate 250 mg in 5 ml saline in Group A and ketamine 50 mg in 5 ml saline nebulization in Group B before the start of general anesthesia. All patients received standard anesthesia protocol. After extubation, all patients were enquired about the incidence and severity of sore throat at 0, 2, 4, 6, and 24 h. Statistical Analysis Used: Paired t -test and Wilcoxon signed-rank test were used to compare hemodynamic variables and Chi-square test to compare the incidence and severity of sore throat. Results: There were no differences in the demographic profile, duration of laryngoscopy, time taken to intubate, and duration of surgery between the two groups. The incidence and severity of sore throat were significantly decreased in ketamine group at 4 and 6 h when compared to magnesium sulfate group. Conclusion: Nebulization with ketamine 50 mg significantly decreases the incidence of POST when compared to magnesium sulfate 250 mg. Competing Interests: There are no conflicts of interest. |
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| فهرسة مساهمة: | Keywords: Endotracheal intubation; general anesthesia; ketamine; magnesium sulfate; nebulization; postoperative sore throat |
| تواريخ الأحداث: | Date Created: 20190122 Latest Revision: 20220331 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC6319074 |
| DOI: | 10.4103/aer.AER_148_18 |
| PMID: | 30662125 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0259-1162 |
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| DOI: | 10.4103/aer.AER_148_18 |