دورية أكاديمية
Male Meiotic Recombination in the Steppe Agama, Trapelus sanguinolentus (Agamidae, Iguania, Reptilia).
| العنوان: | Male Meiotic Recombination in the Steppe Agama, Trapelus sanguinolentus (Agamidae, Iguania, Reptilia). |
|---|---|
| المؤلفون: | Lisachov AP, Tishakova KV, Tsepilov YA, Borodin PM |
| المصدر: | Cytogenetic and genome research [Cytogenet Genome Res] 2019; Vol. 157 (1-2), pp. 107-114. Date of Electronic Publication: 2019 Jan 25. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: S. Karger Country of Publication: Switzerland NLM ID: 101142708 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1424-859X (Electronic) Linking ISSN: 14248581 NLM ISO Abbreviation: Cytogenet Genome Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel ; New York : S. Karger, c2002- |
| مواضيع طبية MeSH: | Homologous Recombination*, Lizards/*genetics , Meiosis/*genetics , Synaptonemal Complex/*genetics, Animals ; Centromere/genetics ; Crossing Over, Genetic/genetics ; Genome Size ; Karyotype ; Lizards/classification ; Male ; MutL Protein Homolog 1/genetics ; Species Specificity |
| مستخلص: | Meiotic recombination rates and patterns of crossover distributions along the chromosomes vary considerably even between closely related species. The adaptive significance of these differences is still unclear due to the paucity of empirical data. Most data on recombination come from mammalian species, while other vertebrate clades are poorly explored. Using immunolocalization of the protein of the lateral element of the synaptonemal complex (SYCP3) and the mismatch-repair protein MLH1, which marks mature recombination nodules, we analyzed recombination rates and crossover distribution in meiotic prophase chromosomes of the steppe agama (Trapelus sanguinolentus, Agamidae, Acrodonta, Iguania) and compared them with data obtained for the genus Anolis (Dactyloidae, Pleurodonta, Iguania). We found that, despite a smaller genome size, the total SC length and the MLH1 focus number per cell are much higher in the agama than in the anoles. The distributions of the MLH1 foci in the agama are multimodal in larger chromosomes and bimodal in smaller chromosomes without a significant centromere effect, resembling the patterns known for birds. A possible relationship between karyotype remodeling and the evolution of recombination in Iguania is discussed. (© 2019 S. Karger AG, Basel.) |
| فهرسة مساهمة: | Keywords: Immunolocalization; MLH1 foci; Meiotic recombination; Steppe agama |
| المشرفين على المادة: | EC 3.6.1.3 (MutL Protein Homolog 1) |
| تواريخ الأحداث: | Date Created: 20190125 Date Completed: 20190528 Latest Revision: 20190528 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1159/000496078 |
| PMID: | 30677759 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1424-859X |
|---|---|
| DOI: | 10.1159/000496078 |